IGFBP2

IGFBP2，即胰島素樣生長(zhǎng)因子結(jié)合蛋白2，別名IGFBP-2、IBP-2等。它是由IGFBP2基因編碼的蛋白質(zhì)，在多種細(xì)胞和組織中廣泛表達(dá)。IGFBP2的主要作用機(jī)制是通過(guò)與胰島素樣生長(zhǎng)因子（IGF）結(jié)合，調(diào)節(jié)IGF的生物可用性，影響細(xì)胞的生長(zhǎng)、分化和凋亡。此外，IGFBP2還能通過(guò)影響細(xì)胞周期和抑制細(xì)胞增殖來(lái)發(fā)揮其生物學(xué)功能。它參與了細(xì)胞增殖、細(xì)胞遷移、組織修復(fù)和腫瘤發(fā)展等過(guò)程。IGFBP2的異常表達(dá)與多種疾病相關(guān)，尤其是在腫瘤生物學(xué)中，IGFBP2的高表達(dá)與腫瘤的侵襲性和預(yù)后不良有關(guān)。因此，IGFBP2是腫瘤治療研究中的一個(gè)潛在靶點(diǎn)。

熱銷產(chǎn)品

IGFBP2 Recombinant Monoclonal Antibody (CSB-RA225697A0HU)

驗(yàn)證數(shù)據(jù)

Western Blot
Positive WB detected in: MCF-7 whole cell lysate
All lanes: IGFBP2 antibody at 1:1000
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 35 kDa
Observed band size: 35 kDa

IHC image of CSB-RA225697A0HU diluted at 1:100 and staining in paraffin-embedded human breast cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4℃ overnight. The primary is detected by a Goat anti-rabbit IgG polymer labeled by HRP and visualized using 0.05% DAB.

IGFBP2 Antibody

IGFBP2 Protein

IGFBP2 ELISA Kit

IGFBP2 Antibodies

IGFBP2 for Homo sapiens (Human)

產(chǎn)品貨號(hào)	產(chǎn)品名稱	種屬反應(yīng)性	應(yīng)用類型
CSB-PA011096GA01HU	IGFBP2 Antibody	Human,Mouse,Rat	ELISA,WB,IHC
CSB-RA225697A0HU	IGFBP2 Recombinant Monoclonal Antibody	Human	ELISA, WB, IHC

IGFBP2 Proteins

IGFBP2 Proteins for Homo sapiens (Human)

產(chǎn)品貨號(hào)	產(chǎn)品名稱	來(lái)源
CSB-YP011096HU CSB-EP011096HU CSB-BP011096HU CSB-MP011096HU CSB-EP011096HU-B	Recombinant Human Insulin-like growth factor-binding protein 2 (IGFBP2)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli