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HCRTR1

HCRTR1,即下丘腦神經肽orexin受體1,別名Ox1-R。攝食行為、睡眠-覺醒周期、應激反應等多種生理功能相關。HCRTR1的作用機制是通過與下丘腦神經肽orexin A的結合,激活G蛋白偶聯的信號傳導途徑,影響下游的細胞內信號級聯反應。HCRTR1在調節睡眠、覺醒、能量代謝以及對應激的響應等方面發揮重要作用。此外,HCRTR1的功能異常與多種疾病相關,包括失眠、嗜睡癥、肥胖等,因此它也是藥物開發中的潛在靶點。

熱銷產品

Recombinant Human Orexin/Hypocretin receptor type 1 (HCRTR1), partial (CSB-YP010231HU1)

驗證數據

CSB-YP010231HU1

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

HCRTR1 Antibody (CSB-PA797469)

驗證數據

CSB-PA797469

The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using CSB-PA797469(HCRTR1 Antibody) at dilution 1/70, on the right is treated with synthetic peptide. (Original magnification: ×200)

CSB-PA797469

The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using CSB-PA797469(HCRTR1 Antibody) at dilution 1/70, on the right is treated with synthetic peptide. (Original magnification: ×200)

HCRTR1 Antibodies

HCRTR1 for Homo sapiens (Human)

HCRTR1 Proteins

HCRTR1 Proteins for Mus musculus (Mouse)

HCRTR1 Proteins for Rattus norvegicus (Rat)

HCRTR1 Proteins for Sus scrofa (Pig)

HCRTR1 Proteins for Bos taurus (Bovine)

HCRTR1 Proteins for Homo sapiens (Human)