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GFRA4

GFRA4,全稱為GDNF家族受體α-4,也被稱為 persephin 受體。它是一種細(xì)胞表面受體,與persephin結(jié)合,并介導(dǎo)RET酪氨酸激酶受體的激活。GFRA4在成人甲狀腺中表達(dá)量較高,同時在胎兒腎上腺和甲狀腺中也有低水平表達(dá)。該蛋白與多種疾病相關(guān),如Hirschsprung病,可能與神經(jīng)系統(tǒng)的發(fā)育和功能有關(guān)。目前,針對GFRA4的抗體產(chǎn)品已研發(fā)出來,用于研究和治療相關(guān)疾病。此外,GFRA4也是藥物研發(fā)的熱點靶點之一,未來可能會有更多針對該蛋白的藥物問世。

熱銷產(chǎn)品

GFRA4 Antibody (CSB-PA271998)

驗證數(shù)據(jù)

CSB-PA271998

The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using CSB-PA271998(GFRA4 Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: ×200)

CSB-PA271998

The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CSB-PA271998(GFRA4 Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: ×200)

GFRA4 Antibodies

GFRA4 for Homo sapiens (Human)

GFRA4 Proteins

GFRA4 Proteins for Homo sapiens (Human)