GBA1
GBA1，即溶酶體酸性β-葡糖腦苷脂酶，是一種在人體細(xì)胞中廣泛分布的酶，尤其在神經(jīng)元和巨噬細(xì)胞中表達(dá)豐富。其結(jié)構(gòu)包含多個(gè)功能域，共同協(xié)作催化葡糖腦苷脂的水解，從而維持細(xì)胞內(nèi)外葡萄糖和腦苷脂的平衡。GBA1不僅參與脂質(zhì)代謝，對(duì)細(xì)胞膜的結(jié)構(gòu)和功能以及細(xì)胞內(nèi)的信號(hào)傳導(dǎo)起到關(guān)鍵作用，還與神經(jīng)系統(tǒng)的正常功能緊密相連。其功能的異常可能導(dǎo)致神經(jīng)退行性疾病如高雪氏癥等的發(fā)生。此外，GBA1與磷脂酰肌醇-3-激酶信號(hào)通路、自噬過(guò)程和炎癥反應(yīng)等細(xì)胞內(nèi)的多個(gè)信號(hào)通路密切相關(guān)，共同調(diào)控細(xì)胞的生長(zhǎng)、增殖、凋亡以及免疫應(yīng)答等生理過(guò)程。
熱銷產(chǎn)品
Recombinant Human Lysosomal acid glucosylceramidase (GBA1)
驗(yàn)證數(shù)據(jù)
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Based on the SEQUEST from database of E.coli host and target protein, the LC-MS/MS Analysis result of CSB-EP009289HU could indicate that this peptide derived from E.coli-expressed Homo sapiens (Human) GBA.
Based on the SEQUEST from database of E.coli host and target protein, the LC-MS/MS Analysis result of CSB-EP009289HU could indicate that this peptide derived from E.coli-expressed Homo sapiens (Human) GBA.
GBA1 Antibodies
GBA1 for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
|---|---|---|---|
| CSB-PA009289GA01HU | GBA Antibody | Human | ELISA,IHC |
| CSB-PA009289LA01HU | GBA Antibody | Human | ELISA, WB, IHC |
| CSB-PA009289LB01HU | GBA Antibody, HRP conjugated | Human | ELISA |
| CSB-PA009289LC01HU | GBA Antibody, FITC conjugated | Human | |
| CSB-PA009289LD01HU | GBA Antibody, Biotin conjugated | Human | ELISA |
| CSB-RA869334A0HU | GBA Recombinant Monoclonal Antibody | Human, Rat, Mouse | ELISA, WB |
GBA1 Proteins
GBA1 Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-BP009289HU CSB-MP009289HU CSB-EP009289HU-B |
Recombinant Human Lysosomal acid glucosylceramidase (GBA1) | Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-EP009289HU | Recombinant Human Lysosomal acid glucosylceramidase (GBA1) | E.coli |
| CSB-EP009289HUb0 | Recombinant Human Lysosomal acid glucosylceramidase (GBA1) | E.coli |
| CSB-EP009289HUe1 | Recombinant Human Lysosomal acid glucosylceramidase (GBA1) | E.coli |
| CSB-BP009289HU(M) | Recombinant Human Lysosomal acid glucosylceramidase (GBA1) (N409S) | Baculovirus |
| CSB-YP009289HU | Recombinant Human Glucosylceramidase (GBA) | Yeast |
| CSB-BP009289HUd7 | Recombinant Human Lysosomal acid glucosylceramidase (GBA1 ) | Baculovirus |
| CSB-EP009289HUa2 | Recombinant Human Lysosomal acid glucosylceramidase (GBA1) | E.coli |
GBA1 ELISA Kit
GBA1 ELISA Kit for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 樣本類型 | 靈敏度 |
|---|---|---|---|
| CSB-EL009289HU | Human Glucosylceramidase(GBA) ELISA kit | serum, plasma, tissue homogenates | 0.078 ng/mL |
