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GABRA1

GABRA1,即γ-氨基丁酸A型受體亞單位α1,別名EJM、ECA4、EJM5、DEE19、EIEE19等。GABRA1基因位于人類第5號染色體上,編碼的蛋白質是GABAA受體α1亞單位,這是一種配體門控的氯離子通道,主要在中樞神經系統中起作用。GABRA1的作用機制是通過與GABA結合,調節氯離子通道的開啟,導致神經元細胞膜的超極化,從而降低神經元的興奮性,產生抑制性突觸后電位。GABRA1在生物學意義上非常重要,它參與調節神經系統的興奮性,對于維持神經系統的正常功能至關重要。GABRA1基因的突變與某些類型的癲癇如青少年肌陣攣性癲癇和兒童失神性癲癇有關,是研究癲癇等疾病的重要靶點。

熱銷產品

Recombinant Human Gamma-aminobutyric acid receptor subunit alpha-1 (GABRA1), partial (CSB-EP009140HU)

驗證數據

CSB-EP009140HU

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

GABRA1 Antibody (CSB-PA100614)

驗證數據

CSB-PA100614

The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CSB-PA100614(GABRA1 Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: ×200)

CSB-PA100614

The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using CSB-PA100614(GABRA1 Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: ×200)

CSB-PA100614

Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane 1-2: Human stomach cancer tissue, LoVo cells, Primary antibody: CSB-PA100614(GABRA1 Antibody) at dilution 1/200, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 10 minutes

GABRA1 Antibodies

GABRA1 for Homo sapiens (Human)

GABRA1 Proteins

GABRA1 Proteins for Homo sapiens (Human)