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FOLR2

FOLR2,全稱為葉酸受體β(Folate Receptor Beta),也被稱為FBP、FOLR2、BETA-HFR、FBP/PL-1、FR-BETA、FR-P3和FR-P4。該蛋白屬于葉酸受體(FOLR)家族,主要存在于胎盤、中性粒細胞譜系細胞和部分CD34+造血祖細胞中。FOLR2蛋白原本被認為僅存在于胎盤中,但后來發現也存在于脾臟、骨髓和胸腺。它在惡性腫瘤、頭頸鱗狀細胞癌和多種非上皮性癌癥中表達上調,尤其是在單核細胞和巨噬細胞中。FOLR2蛋白是M-CSF生成的巨噬細胞的標志物,其表達與葉酸攝取能力的增加相關。葉酸綴合的藥物是靶向腫瘤相關巨噬細胞的潛在免疫療法工具。

熱銷產品

Recombinant Human Folate receptor beta (FOLR2), partial (CSB-BP008786HU1)

驗證數據

CSB-BP008786HU1

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

FOLR2 Antibody (CSB-PA008786LA01HU)

驗證數據

CSB-PA008786LA01HU

IHC image of CSB-PA008786LA01HU diluted at 1:400 and staining in paraffin-embedded human placenta tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.

CSB-PA008786LA01HU

Immunofluorescence staining of Hela cells with CSB-PA008786LA01HU at 1:133, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).

FOLR2 Antibodies

FOLR2 for Homo sapiens (Human)

FOLR2 Proteins

FOLR2 Proteins for Homo sapiens (Human)



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