F2RL1
F2RL1，全稱為F2R like trypsin receptor 1，常見(jiàn)別名包括GPR11和PAR2。該蛋白屬于G蛋白偶聯(lián)受體家族，主要表達(dá)于胃腸道和平滑肌中，在血漿膜上定位。F2RL1蛋白的表達(dá)受多種蛋白酶調(diào)控，如胰蛋白酶和胰蛋白酶樣酶，這些蛋白酶的切割激活該受體，進(jìn)而參與炎癥反應(yīng)、血管舒張、血壓調(diào)節(jié)等生理過(guò)程。F2RL1蛋白還與多種疾病的發(fā)生發(fā)展密切相關(guān)，包括腎癌、肺癌、特應(yīng)性皮炎和哮喘等。目前，針對(duì)F2RL1蛋白的藥物研發(fā)主要集中在抑制其表達(dá)或阻斷其信號(hào)通路，以期治療相關(guān)疾病。例如，有研究開(kāi)發(fā)了一種靶向F2RL1蛋白的RNA復(fù)合物，通過(guò)抑制F2RL1蛋白的表達(dá)來(lái)治療特應(yīng)性皮炎和哮喘。此外，F(xiàn)2RL1蛋白也被認(rèn)為是一種潛在的腫瘤標(biāo)志物，可用于結(jié)直腸癌和宮頸癌的診斷與預(yù)后評(píng)估。
熱銷(xiāo)產(chǎn)品
F2RL1 Antibody (CSB-PA007925LA01HU)
驗(yàn)證數(shù)據(jù)
Immunohistochemistry of paraffin-embedded human small intestine tissue using CSB-PA007925LA01HU at dilution of 1:100
Immunofluorescent analysis of A549 cells using CSB-PA007925LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
F2RL1 Antibodies
F2RL1 for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類(lèi)型 |
|---|---|---|---|
| CSB-PA007925GA01HU | F2RL1 Antibody | Human,Mouse,Rat | ELISA,WB |
| CSB-PA007925LA01HU | F2RL1 Antibody | Human | ELISA, IHC, IF |
| CSB-PA007925LB01HU | F2RL1 Antibody, HRP conjugated | Human | ELISA |
| CSB-PA007925LC01HU | F2RL1 Antibody, FITC conjugated | Human | |
| CSB-PA007925LD01HU | F2RL1 Antibody, Biotin conjugated | Human | ELISA |
F2RL1 Proteins
F2RL1 Proteins for Mus musculus (Mouse)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP007925MO1 CSB-EP007925MO1 CSB-BP007925MO1 CSB-MP007925MO1 CSB-EP007925MO1-B |
Recombinant Mouse Proteinase-activated receptor 2 (F2rl1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF007925MO | Recombinant Mouse Proteinase-activated receptor 2 (F2rl1) | in vitro E.coli expression system |
F2RL1 Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP007925HU1 CSB-EP007925HU1 CSB-BP007925HU1 CSB-MP007925HU1 CSB-EP007925HU1-B |
Recombinant Human Proteinase-activated receptor 2 (F2RL1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF007925HU | Recombinant Human Proteinase-activated receptor 2 (F2RL1) | in vitro E.coli expression system |
F2RL1 Proteins for Bos taurus (Bovine)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP643165BO1 CSB-EP643165BO1 CSB-BP643165BO1 CSB-MP643165BO1 CSB-EP643165BO1-B |
Recombinant Bovine Proteinase-activated receptor 2 (F2RL1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF643165BO | Recombinant Bovine Proteinase-activated receptor 2 (F2RL1) | in vitro E.coli expression system |
F2RL1 Proteins for Rattus norvegicus (Rat)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP737213RA1 CSB-EP737213RA1 CSB-BP737213RA1 CSB-MP737213RA1 CSB-EP737213RA1-B |
Recombinant Rat Proteinase-activated receptor 2 (F2rl1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF737213RA | Recombinant Rat Proteinase-activated receptor 2 (F2rl1) | in vitro E.coli expression system |
