DDX53
DDX53,全稱為DEAD-box解旋酶53,常見別名包括HEL117。這種蛋白能解開RNA的雙鏈結構,在細胞里參與RNA的加工和轉運,幫著維持基因表達的正常節奏。一旦DDX53的表達量或功能出了問題,可能會打亂細胞內的分子平衡,和一些疾病掛上鉤。比如在前列腺癌、非小細胞肺癌患者的組織樣本里,它的含量往往比正常細胞高很多,可能助推腫瘤細胞生長和擴散,算是這些癌癥里一個潛在的標記物。現在針對它的藥物研究還在早期,科學家們試著開發能抑制它功能的小分子化合物,希望通過瞄準它阻止腫瘤發展。
熱銷產品
Recombinant Human Probable ATP-dependent RNA helicase DDX53 (DDX53) (CSB-EP773024HU)
驗證數據
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Based on the SEQUEST from database of E.coli host and target protein, the LC-MS/MS Analysis result of CSB-EP773024HU could indicate that this peptide derived from E.coli-expressed Homo sapiens (Human) DDX53.
Based on the SEQUEST from database of E.coli host and target protein, the LC-MS/MS Analysis result of CSB-EP773024HU could indicate that this peptide derived from E.coli-expressed Homo sapiens (Human) DDX53.
驗證數據
The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using CSB-PA801951(DDX53 Antibody) at dilution 1/75, on the right is treated with fusion protein. (Original magnification: ×200)
The image on the left is immunohistochemistry of paraffin-embedded Human gastric cancer tissue using CSB-PA801951(DDX53 Antibody) at dilution 1/75, on the right is treated with fusion protein. (Original magnification: ×200)
Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane: HepG2 cells, Primary antibody: CSB-PA801951(DDX53 Antibody) at dilution 1/200, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1 minute
DDX53 Antibodies
DDX53 for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 種屬反應性 | 應用類型 |
|---|---|---|---|
| CSB-PA801951 | DDX53 Antibody | Human | ELISA,WB,IHC |
| CSB-PA343705 | DDX53 Antibody | Human | ELISA,WB,IHC |
DDX53 Proteins
DDX53 Proteins for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP773024HU CSB-BP773024HU CSB-MP773024HU CSB-EP773024HU-B |
Recombinant Human Probable ATP-dependent RNA helicase DDX53 (DDX53) | Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-EP773024HU | Recombinant Human Probable ATP-dependent RNA helicase DDX53 (DDX53) | E.coli |






