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DDX5

DDX5,即DEAD盒解旋酶5,別名P68。它是一種依賴ATP的RNA解旋酶,屬于DEAD盒解旋酶家族成員之一,主要分布在細胞核內。DDX5的作用機制涉及催化雙鏈RNA解旋,參與基因轉錄的正負調節以及mRNA、rRNA和miRNA的合成、剪接和加工等過程。DDX5對多種轉錄因子具有激活作用,影響細胞增殖、分化、細胞骨架重塑和細胞凋亡等,同時在腫瘤細胞的發生、侵襲和遷移中發揮作用,是影響腫瘤相關信號通路的關鍵因子。此外,DDX5的功能缺失可通過影響microRNA 125b的表達水平,上調非經典PRC1復合物里的RYBP,進而影響體細胞重編程過程。

熱銷產品

Recombinant Human Probable ATP-dependent RNA helicase DDX5 (DDX5) (CSB-EP006630HU)

驗證數據

CSB-EP006630HU

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

CSB-EP006630HU

Based on the SEQUEST from database of E.coli host and target protein, the LC-MS/MS Analysis result of CSB-EP006630HU could indicate that this peptide derived from E.coli-expressed Homo sapiens (Human) DDX5.

CSB-EP006630HU

Based on the SEQUEST from database of E.coli host and target protein, the LC-MS/MS Analysis result of CSB-EP006630HU could indicate that this peptide derived from E.coli-expressed Homo sapiens (Human) DDX5.

DDX5 Antibody (CSB-PA003685)

驗證數據

CSB-PA003685

Western Blot analysis of HepG2 cells using p68 RNA Helicase Polyclonal Antibody

DDX5 Antibodies

DDX5 for Homo sapiens (Human)

DDX5 Proteins

DDX5 Proteins for Homo sapiens (Human)