CRL5
CRL5,別名CUL-5、Vasopressin-activated calcium-mobilizing receptor 1、VACM-1,它是一個多亞基組成的蛋白復合物。CRL5來源于細胞內,由骨架蛋白Cullin 5、RING蛋白SAG、銜接蛋白Elongin B/C和底物識別蛋白SOCS等多個組分構成。其作用機制主要通過靶向降解一系列關鍵調節蛋白或改變蛋白互相作用方式,參與細胞因子信號傳導、炎癥反應、病毒感染、腫瘤發生等生物學過程。CRL5作為E3泛素連接酶的重要成員,通過精細調控蛋白質的穩定性和活性,維持細胞內環境的穩定,對生物體的正常生理功能和疾病發生發展具有深遠影響。
熱銷產品
Recombinant Human Cullin-5 (CUL5) (CSB-EP835890HU)
驗證數據
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
CUL5 Antibody (CSB-PA835890ESR1HU)
驗證數據
Immunohistochemistry of paraffin-embedded human tonsil tissue using CSB-PA835890ESR1HU at dilution of 1:100
Immunohistochemistry of paraffin-embedded human kidney tissue using CSB-PA835890ESR1HU at dilution of 1:100
CRL5 Antibodies
CRL5 for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 種屬反應性 | 應用類型 |
|---|---|---|---|
| CSB-PA835890ESR1HU | CUL5 Antibody | Human | ELISA, IHC |
| CSB-PA835890ESR2HU | CUL5 Antibody | Human | ELISA, IHC |
| CSB-PA113726 | CUL5 Antibody | Human,Mouse,Rat | ELISA,IHC |
CRL5 Proteins
CRL5 Proteins for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP835890HU CSB-BP835890HU CSB-MP835890HU CSB-EP835890HU-B |
Recombinant Human Cullin-5 (CUL5) | Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-EP835890HU | Recombinant Human Cullin-5 (CUL5) | E.coli |






