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CKAP4

CKAP4,即細胞骨架相關蛋白4,別名p63、CLIMP63、ERGIC-63。CKAP4是一種II型跨膜蛋白,主要定位于細胞膜和粗面內質網,同時也是多種配體的受體,在穩定蛋白結構中發揮重要作用。CKAP4參與多種生物活動,包括細胞增殖、細胞遷移、角質形成細胞分化、糖生成、纖維化、胸腺發育、心臟發生、神經元凋亡和癌癥的發生發展。CKAP4及其亞型與DKK1或DKK3(Dickkopf蛋白)或抗增殖因子(APF)結合,并調節多個下游信號通路,如PI3K/AKT和MAPK1/3。CKAP4復合體在調節信號通路中起關鍵作用,是癌癥治療的潛在靶點。

熱銷產品

CKAP4 Antibody (CSB-PA005453LA01HU)

驗證數據

CSB-PA005453LA01HU

Western Blot
Positive WB detected in: HepG2 whole cell lysate, Hela whole cell lysate
All lanes: CKAP4 antibody at 2.7µg/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 67 kDa
Observed band size: 67 kDa

CSB-PA005453LA01HU

Immunofluorescence staining of Hela cells with CSB-PA005453LA01HU at 1:133, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).

Human Cytoskeleton-associated protein 4(CKAP4) ELISA kit (CSB-EL005453HU)

驗證數據

CSB-EL005453HU 標準曲線

貨號:CSB-EL005453HU

規格:96T/48T

靈敏度:5.86 pg/mL

檢測范圍:23.44 pg/mL-1500 pg/mL

These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

CKAP4 Antibodies

CKAP4 for Homo sapiens (Human)

CKAP4 Proteins

CKAP4 Proteins for Mus musculus (Mouse)

CKAP4 ELISA Kit

CKAP4 ELISA Kit for Homo sapiens (Human)



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