CIAO3
CIAO3，全稱為cytosolic iron-sulfur assembly component 3，在生物體內(nèi)扮演著重要的角色。該蛋白也被稱為HPRN、IOP1、LET1L、NAR1、NARFL和PRN等。CIAO3蛋白參與細(xì)胞內(nèi)的鐵硫簇組裝過(guò)程，是細(xì)胞鐵硫蛋白生物合成不可或缺的一部分。它與其他蛋白形成復(fù)合體，共同促進(jìn)鐵硫簇的正確組裝，進(jìn)而影響細(xì)胞內(nèi)鐵代謝和氧化應(yīng)激反應(yīng)。研究表明，CIAO3蛋白可能參與調(diào)節(jié)HIF1A的表達(dá)水平，盡管這種影響可能是間接的。此外，CIAO3蛋白還與多種疾病的發(fā)生發(fā)展相關(guān)，如肺動(dòng)脈畸形等。目前，針對(duì)CIAO3蛋白的功能和作用機(jī)制仍在深入研究中，相關(guān)藥物研發(fā)也處于探索階段。科學(xué)家們希望通過(guò)研究CIAO3蛋白，能夠開(kāi)發(fā)出治療相關(guān)疾病的新藥，為患者帶來(lái)新的希望。
熱銷產(chǎn)品
CIAO3 Antibody (CSB-PA863991LA01HU)
驗(yàn)證數(shù)據(jù)
Western Blot
Positive WB detected in: A549 whole cell lysate
All lanes: CIAO3 antibody at 2.7µg/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 54, 27, 43 kDa
Observed band size: 54, 27 kDa
Immunohistochemistry of paraffin-embedded human colon cancer using CSB-PA863991LA01HU at dilution of 1:100
Immunofluorescent analysis of U251 cells using CSB-PA863991LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
CIAO3 Antibodies
CIAO3 for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
|---|---|---|---|
| CSB-PA015455GA01HU | NARFL Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
| CSB-PA160212 | NARFL Antibody | Human | ELISA,WB |
| CSB-PA003370 | NARFL Antibody | Human | WB, IHC, ELISA |
| CSB-PA863991LA01HU | CIAO3 Antibody | Human | ELISA, WB, IHC, IF |
| CSB-PA863991LB01HU | CIAO3 Antibody, HRP conjugated | Human | ELISA |
| CSB-PA863991LC01HU | CIAO3 Antibody, FITC conjugated | Human | |
| CSB-PA863991LD01HU | CIAO3 Antibody, Biotin conjugated | Human | ELISA |
CIAO3 Proteins
CIAO3 Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP863991HU CSB-EP863991HU CSB-BP863991HU CSB-MP863991HU CSB-EP863991HU-B |
Recombinant Human Cytosolic Fe-S cluster assembly factor NARFL (NARFL) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
