国产午夜福利片1000无码丨人妻国产成人久久av免费高清丨午夜做受视频试看6次丨日韩av不卡一区在线免费观看丨在线观看精品三级欧美

Your Good Partner in Biology Research

CHD8

Chromodomain-helicase-DNA-binding protein 8 is a protein in humans that is encoded by CHD8 gene. DNA helicase that acts as a chromatin remodeling factor and regulates transcription. Acts as a transcription repressor by remodeling chromatin structure and recruiting histone H1 to target genes. Suppresses p53/TP53-mediated apoptosis by recruiting histone H1 and preventing p53/TP53 transactivation activity. Acts as a negative regulator of Wnt signaling pathway by regulating beta-catenin (CTNNB1) activity. Negatively regulates CTNNB1-targeted gene expression by being recruited specifically to the promoter regions of several CTNNB1 responsive genes. Involved in both enhancer blocking and epigenetic remodeling at chromatin boundary via its interaction with CTCF. Acts as a suppressor of STAT3 activity by suppressing the LIF-induced STAT3 transcriptional activity. Also acts as a transcription activator via its interaction with ZNF143 by participating in efficient U6 RNA polymerase III transcription.

CHD8 Proteins

CHD8 Proteins for Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)

CHD8 Proteins for Danio rerio (Zebrafish) (Brachydanio rerio)

CHD8 Proteins for Homo sapiens (Human)

CHD8 Proteins for Rattus norvegicus (Rat)



主站蜘蛛池模板: 大新县| 莒南县| 揭东县| 东光县| 邳州市| 中牟县| 广安市| 内丘县| 揭西县| 家居| 临沭县| 山丹县| 淮滨县| 威海市| 海林市| 郑州市| 元氏县| 五大连池市| 图们市| 阿瓦提县| 双城市| 奉贤区| 玉山县| 塔河县| 宜都市| 西安市| 武宣县| 木里| 辉南县| 昌都县| 萝北县| 隆德县| 壶关县| 尉犁县| 乃东县| 习水县| 渭源县| 宜君县| 台东县| 华阴市| 南汇区|