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CDCP1

CDCP1,CUB結構域包含蛋白1,別名CD318、UNQ2486、PRO5773,由人類CDCP1基因編碼。CDCP1是一種I型跨膜糖蛋白,主要位于細胞表面,并參與多個腫瘤發生和轉移的關鍵信號通路,包括SRC/PKCd、PI3K/AKT、WNT和RAS/ERK軸、氧化戊糖磷酸途徑和脂肪酸氧化等,對癌細胞生存、生長、轉移以及治療的耐藥性有重要意義。CDCP1的作用機制涉及與多種癌癥相關蛋白的相互作用,并在腫瘤標志物和潛在的治療靶點中發揮作用。CDCP1在多種惡性腫瘤中過表達,包括呼吸腫瘤、消化系統癌癥、血液學惡性腫瘤和泌尿生殖系統癌癥,與腫瘤的預后和藥物抗性相關,被認為是一個有前景的治療靶點和新的診斷生物標志物。

熱銷產品

Recombinant Human CUB domain-containing protein 1 (CDCP1), partial (Active) (CSB-MP884474HU)

驗證數據

CSB-MP884474HU

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

CSB-MP884474HU

Activity
Measured by its binding ability in a functional ELISA. Immobilized Human CDCP1 at 2μg/mL can bind Anti-CDCP1 recombinant antibody (CSB-RA884474MA1HU),the EC50 is 0.2943-0.4429 ng/mL.

Recombinant Mouse CUB domain-containing protein 1 (Cdcp1), partial (Active) (CSB-MP719456MO)

驗證數據

CSB-MP719456MO

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

CSB-MP719456MO

Activity
Measured by its binding ability in a functional ELISA. Immobilized Mouse Cdcp1 at 2 μg/mL can bind Anti-CDCP1 recombinant antibody (CSB-RA884474MA1HU), the EC50 is 0.6397-0.8369 ng/mL.

Recombinant Macaca fascicularis CUB domain containing protein 1 (CDCP1), partial (Active) (CSB-MP4569MOV)

驗證數據

CSB-MP4569MOV

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

CSB-MP4569MOV

Activity
Measured by its binding ability in a functional ELISA. Immobilized Macaca fascicularis CDCP1 at 2μg/mL can bind Anti-CDCP1 recombinant antibody (CSB-RA884474MA1HU),the EC50 is 1.861-2.330 ng/mL.

CDCP1 Antibody (CSB-PA884474ESR2HU)

驗證數據

CSB-PA884474ESR2HU

Immunohistochemistry of paraffin-embedded human endometrial cancer using CSB-PA884474ESR2HU at dilution of 1:100

CDCP1 Antibodies

CDCP1 for Homo sapiens (Human)

CDCP1 Proteins

CDCP1 Proteins for Mus musculus (Mouse)

CDCP1 Proteins for Homo sapiens (Human)



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