CD2
CD2，全稱為CD2抗原，是一種在免疫細胞表面表達的蛋白質，屬于免疫球蛋白超家族成員。CD2蛋白在T細胞的發(fā)育、激活和功能中發(fā)揮著重要作用。CD2蛋白的常見別名包括LFA-1（淋巴細胞功能相關抗原-1）和T10。CD2蛋白通過與CD58蛋白結合，參與T細胞與抗原呈遞細胞的粘附過程，從而激活T細胞并啟動免疫應答。CD2蛋白還與CD4和CD8分子的表達相關，參與T細胞的分化和功能調節(jié)。CD2蛋白的表達異常與某些自身免疫性疾病和腫瘤相關。目前，針對CD2蛋白的藥物研發(fā)主要集中在免疫治療領域，例如CD2單克隆抗體和雙特異性抗體，用于治療癌癥和自身免疫性疾病。
熱銷產品
Recombinant Human T-cell surface antigen CD2 (CD2), partial (Active) (CSB-MP004894HU)
驗證數據
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Activity
Measured by its binding ability in a functional ELISA. Immobilized Human CD2 at 5 μg/ml can bind Human CD58(CSB-MP6138HUj8-B). The EC50 is 337.0-430.1 ng/mL.
The purity of CD2 was greater than 95% as determined by SEC-HPLC
Recombinant Human T-cell surface antigen CD2 (CD2), partial (CSB-EP004894HU)
驗證數據
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
CD2 Recombinant Monoclonal Antibody (CSB-RA911142A0HU)
驗證數據
Western Blot
Positive WB detected in: HepG2 whole cell lysate(30μg), COLO205 whole cell lysate(30μg), MCF-7 whole cell lysate(30μg)
All lanes: CD2 antibody at 1:1000
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 39 kDa
Observed band size: 24 kDa
Exposure time: 3min
CD2 Antibodies
CD2 for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 種屬反應性 | 應用類型 |
|---|---|---|---|
| CSB-PA004894GA01HU | CD2 Antibody | Human | ELISA,WB |
| CSB-PA004894LA01HU | CD2 Antibody | Human | ELISA, IHC, IF |
| CSB-PA004894LB01HU | CD2 Antibody, HRP conjugated | Human | ELISA |
| CSB-PA005194 | CD2 Antibody | Human | WB, ELISA |
| CSB-RA911142A0HU | CD2 Recombinant Monoclonal Antibody | Human | ELISA, WB |
CD2 for H, M, R
| 產品貨號 | 產品名稱 | 種屬反應性 | 應用類型 |
|---|---|---|---|
| CSB-MA000227 | CD2 Monoclonal Antibody | Human,Mouse,Rat | ELISA,IHC |
CD2 Proteins
CD2 Proteins for Equus caballus (Horse)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP004894HO1 CSB-EP004894HO1 CSB-BP004894HO1 CSB-MP004894HO1 CSB-EP004894HO1-B |
Recombinant Horse T-cell surface antigen CD2 (CD2), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF004894HO | Recombinant Horse T-cell surface antigen CD2 (CD2) | in vitro E.coli expression system |
CD2 Proteins for Rattus norvegicus (Rat)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP004894RA1 CSB-EP004894RA1 CSB-BP004894RA1 CSB-MP004894RA1 CSB-EP004894RA1-B |
Recombinant Rat T-cell surface antigen CD2 (Cd2), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF004894RA | Recombinant Rat T-cell surface antigen CD2 (Cd2) | in vitro E.coli expression system |
CD2 Proteins for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP004894HU CSB-BP004894HU CSB-EP004894HU-B |
Recombinant Human T-cell surface antigen CD2 (CD2), partial | Yeast Baculovirus In Vivo Biotinylation in E.coli |
| CSB-EP004894HU | Recombinant Human T-cell surface antigen CD2 (CD2), partial | E.coli |
| CSB-CF004894HU(A4) | Recombinant Human T-cell surface antigen CD2 (CD2) | in vitro E.coli expression system |
| CSB-MP004894HU(A4)f4 | Recombinant Human T-cell surface antigen CD2 (CD2)-VLPs, Fluorescent | Mammalian cell |
| CSB-MP004894HU | Recombinant Human T-cell surface antigen CD2 (CD2), partial (Active) | Mammalian cell |
CD2 Proteins for Mus musculus (Mouse)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP004894MO1 CSB-EP004894MO1 CSB-BP004894MO1 CSB-MP004894MO1 CSB-EP004894MO1-B |
Recombinant Mouse T-cell surface antigen CD2 (Cd2), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF004894MO | Recombinant Mouse T-cell surface antigen CD2 (Cd2) | in vitro E.coli expression system |
CD2 Proteins for Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP750970MOV CSB-EP750970MOV CSB-BP750970MOV CSB-MP750970MOV CSB-EP750970MOV-B |
Recombinant Macaca fascicularis T-cell surface antigen CD2 (CD2), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
