CCL21
CCL21，即C-C基序趨化因子配體21，別名ECL、SLC、CKb9、TCA4、SCYA21。CCL21是一種小分子細(xì)胞因子，屬于CC亞家族的趨化因子，主要在淋巴管起始處和淋巴器官中組成型表達(dá)，存在于幾種基質(zhì)細(xì)胞和高內(nèi)皮小靜脈（HEV）上，可以與糖胺聚糖（GAG）結(jié)合并固定在內(nèi)皮細(xì)胞表面。CCL21通過與趨化因子受體CCR7和CXCR3結(jié)合，發(fā)揮其生物學(xué)功能。CCL21對(duì)胸腺細(xì)胞和活化的T細(xì)胞具有體外趨化作用，但對(duì)B細(xì)胞、巨噬細(xì)胞或中性粒細(xì)胞沒有趨化作用。CCL21也是一種有效的T細(xì)胞遷移和粘附刺激物，可以促進(jìn)T細(xì)胞向次級(jí)淋巴器官的遷移，對(duì)淋巴細(xì)胞歸巢至二級(jí)淋巴器官中發(fā)揮作用，具有重要的免疫調(diào)節(jié)作用。
熱銷產(chǎn)品
Recombinant Human C-C motif chemokine 21 (CCL21) (CSB-EP004785HUc0)
驗(yàn)證數(shù)據(jù)
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
驗(yàn)證數(shù)據(jù)
The image on the left is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using CSB-PA576836(CCL21 Antibody) at dilution 1/40, on the right is treated with fusion protein. (Original magnification: ×200)
The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using CSB-PA576836(CCL21 Antibody) at dilution 1/40, on the right is treated with fusion protein. (Original magnification: ×200)
CCL21 Antibodies
CCL21 for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
|---|---|---|---|
| CSB-PA004785DA01HU | CCL21 Antibody | Human | ELISA, IHC |
| CSB-PA004785DD01HU | CCL21 Antibody, Biotin conjugated | Human | ELISA |
| CSB-PA004785DC01HU | CCL21 Antibody, FITC conjugated | Human | |
| CSB-PA004785DB01HU | CCL21 Antibody, HRP conjugated | Human | ELISA |
| CSB-PA576836 | CCL21 Antibody | Human | ELISA,IHC |
| CSB-PA929761 | CCL21 Antibody | Human | ELISA,IHC |
CCL21 Proteins
CCL21 Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP004785HU CSB-BP004785HU CSB-MP004785HU CSB-EP004785HU-B |
Recombinant Human C-C motif chemokine 21 (CCL21) | Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-EP004785HU | Recombinant Human C-C motif chemokine 21 (CCL21) | E.coli |
| CSB-AP000941HU | Recombinant Human C-C motif chemokine 21 protein (CCL21) | E.Coli |
| CSB-EP004785HUc0 | Recombinant Human C-C motif chemokine 21 (CCL21) | E.coli |
CCL21 Proteins for Macaca mulatta (Rhesus macaque)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP812822MOW CSB-EP812822MOW CSB-BP812822MOW CSB-MP812822MOW CSB-EP812822MOW-B |
Recombinant Macaca mulatta C-C motif chemokine 21 (CCL21) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CCL21 ELISA Kit
CCL21 ELISA Kit for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 樣本類型 | 靈敏度 |
|---|---|---|---|
| CSB-E04521h | Human secondary lymphoid-tissue chemokine,SLC ELISA Kit | serum, plasma | 19.5 pg/mL |
