BCR
BCR，即B細(xì)胞抗原受體，別名CML、D22S1、D22S662、PHL。它是一種位于B細(xì)胞表面的分子，其本質(zhì)是一種膜表面免疫球蛋白（membrane immunoglobulin, mIg）。BCR通過(guò)與抗原的特異性結(jié)合來(lái)識(shí)別多種類型的抗原，包括蛋白質(zhì)、多肽、核酸、多糖、脂類和小分子化合物。BCR的作用機(jī)制涉及與抗原結(jié)合后，導(dǎo)致BCR復(fù)合物發(fā)生聚合和結(jié)構(gòu)變化，激活細(xì)胞質(zhì)內(nèi)的酪氨酸激酶，進(jìn)而引發(fā)一系列的信號(hào)轉(zhuǎn)導(dǎo)級(jí)聯(lián)反應(yīng)，最終導(dǎo)致基因轉(zhuǎn)錄調(diào)控和B細(xì)胞的增殖、分化。BCR對(duì)抗原的識(shí)別和應(yīng)答是適應(yīng)性免疫反應(yīng)的關(guān)鍵步驟，對(duì)抗體的產(chǎn)生和免疫記憶的形成具有重要意義。
熱銷產(chǎn)品
BCR (Ab-177) Antibody (CSB-PA929167)
驗(yàn)證數(shù)據(jù)
Western blot analysis of extracts from HL60 and K562 cells using Bcr(Ab-177) Antibody.
Immunofluorescence staining of methanol-fixed Hela cells using Bcr(Ab-177) Antibody.
BCR Antibodies
BCR for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
|---|---|---|---|
| CSB-PA899546 | Phospho-BCR (Tyr177) Antibody | Human,Mouse | ELISA,WB,IHC |
| CSB-PA929167 | BCR (Ab-177) Antibody | Human,Mouse | ELISA,WB,IF |
| CSB-PA950927 | Phospho-BCR (Tyr360) Antibody | Human,Mouse | ELISA,WB |
| CSB-PA000486 | Phospho-BCR (Y177) Antibody | Human,Mouse | WB, ELISA |
| CSB-PA000989 | BCR Antibody | Human,Mouse | WB, IHC, ELISA |
| CSB-PA000990 | BCR Antibody | Human,Mouse | WB, IHC, ELISA |
| CSB-PA040236 | Phospho-BCR (Y360) Antibody | Human,Mouse,Monkey | WB, IHC, IF, ELISA |
| CSB-PA552207 | BCR Antibody | Human,Mouse | ELISA,IHC |
| CSB-PA196525 | BCR Antibody | Human,Mouse | ELISA,IHC |
BCR Proteins
BCR Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP002638HU CSB-EP002638HU CSB-BP002638HU CSB-MP002638HU CSB-EP002638HU-B |
Recombinant Human Breakpoint cluster region protein (BCR), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
