国产午夜福利片1000无码丨人妻国产成人久久av免费高清丨午夜做受视频试看6次丨日韩av不卡一区在线免费观看丨在线观看精品三级欧美

Your Good Partner in Biology Research

ATM

ATM,即共濟失調毛細血管擴張癥突變蛋白,別名A-TM。它是一種絲氨酸/蘇氨酸蛋白激酶,屬于PI3K樣蛋白激酶(PIKKs)家族成員之一。ATM主要在細胞核中表達,其編碼基因位于人類第11號染色體上。ATM的作用機制涉及對DNA雙鏈斷裂(DSB)的響應,通過磷酸化多種底物蛋白,包括p53、Chk2、BRCA1等,從而激活細胞周期檢查點、促進DNA修復和誘導細胞凋亡。ATM在維持基因組穩定性、防止腫瘤發生以及對電離輻射和化療藥物的響應中發揮關鍵作用,其功能喪失會導致Ataxia-telangiectasia(A-T)疾病,表現為神經系統退化、癌癥易感性增加和免疫功能障礙。

熱銷產品

ATM Recombinant Monoclonal Antibody (CSB-RA166706A0HU)

驗證數據

CSB-RA166706A0HU

IHC image of CSB-RA166706A0HU diluted at 1:100 and staining in paraffin-embedded human breast cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4℃ overnight. The primary is detected by a Goat anti-rabbit IgG polymer labeled by HRP and visualized using 0.05% DAB.

CSB-RA166706A0HU

IHC image of CSB-RA166706A0HU diluted at 1:100 and staining in paraffin-embedded human testis tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4℃ overnight. The primary is detected by a Goat anti-rabbit IgG polymer labeled by HRP and visualized using 0.05% DAB.

CSB-RA166706A0HU

Overlay histogram showing Hela cells stained with CSB-RA166706A0HU (red line) at 1:50. The cells were fixed with 70% Ethylalcohol (18h) and then incubated in 10% normal goat serum to block non-specific protein-protein interactions followedby the antibody (1μg/1*106 cells) for 1 h at 4℃.The secondary antibody used was FITC-conjugated goat anti-rabbit IgG (H+L) at 1/200 dilution for 30min at 4℃. Control antibody (green line) was Rabbit IgG (1μg/1*106 cells) used under the same conditions. Acquisition of >10,000 events was performed.

ATM Antibodies

ATM for Homo sapiens (Human)

ATM Proteins

ATM Proteins for Homo sapiens (Human)

ATM Proteins for Mus musculus (Mouse)

ATM Proteins for Sus scrofa (Pig)

ATM Proteins for Arabidopsis thaliana (Mouse-ear cress)



主站蜘蛛池模板: 重庆市| 息烽县| 天柱县| 鹤山市| 莒南县| 浏阳市| 双流县| 凤山市| 无棣县| 勐海县| 开原市| 谷城县| 久治县| 永州市| 桐乡市| 东至县| 应城市| 济源市| 三门峡市| 灵璧县| 岳阳市| 崇左市| 内黄县| 翼城县| 循化| 宜春市| 旬邑县| 乐安县| 南丹县| 红桥区| 京山县| 鄂州市| 苍溪县| 中方县| 法库县| 永登县| 彩票| 和政县| 延津县| 凤山县| 巴南区|