ASIP
ASIP，全稱為Agouti-signaling protein，也被稱為刺鼠信號蛋白。該蛋白主要參與調控哺乳動物體內的毛色分布，通過其產物影響天然色素、黑色素等的分布。在犬類中，ASIP基因與許多毛色和毛色模式相關。此外，ASIP蛋白還在黑皮質素作用的神經內分泌方面發揮作用，并可能影響脂肪細胞中的脂質代謝。
ASIP蛋白的相關疾病包括間質性肺炎和自身免疫性疾病。研究表明，ASIP蛋白可與 α-MSH 競爭性結合黑素皮質素受體1(melanocortin 1 receptor, MC1R)，調節真黑色素和褐黑色素生成的數量與比例，從而使動物表現出不同的毛色或膚色。此外，ASIP 蛋白還可能與特發性肺纖維化 (IPF) 等疾病相關。
在藥物研發方面，ASIP蛋白也受到關注。例如，英矽智能公司利用其AI平臺發現了一個新的泛纖維化疾病靶點，并生成了能夠作用于特發性肺纖維化 (IPF) 的新的小分子，該小分子已進入臨床前研究階段。此外，還有研究表明，ASIP蛋白可能與乳腺癌相關，其表達水平可能與乳腺癌患者的預后相關。
熱銷產品
Recombinant Human Agouti-signaling protein (ASIP) (CSB-EP002212HU)
驗證數據
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
ASIP Antibody (CSB-PA002212LA01HU)
驗證數據
Immunohistochemistry of paraffin-embedded human endometrial cancer using CSB-PA002212LA01HU at dilution of 1:100
Immunofluorescent analysis of MCF-7 cells using CSB-PA002212LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
ASIP Antibodies
ASIP for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 種屬反應性 | 應用類型 |
|---|---|---|---|
| CSB-PA002212LA01HU | ASIP Antibody | Human | ELISA, IHC, IF |
| CSB-PA002212LB01HU | ASIP Antibody, HRP conjugated | Human | ELISA |
| CSB-PA002212LD01HU | ASIP Antibody, Biotin conjugated | Human | ELISA |
ASIP Proteins
ASIP Proteins for Mus musculus (Mouse)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP002212MO CSB-EP002212MO CSB-BP002212MO CSB-MP002212MO CSB-EP002212MO-B |
Recombinant Mouse Agouti-signaling protein (Asip) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
ASIP Proteins for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP002212HU CSB-BP002212HU CSB-MP002212HU CSB-EP002212HU-B |
Recombinant Human Agouti-signaling protein (ASIP) | Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-EP002212HU1 | Recombinant Human Agouti-signaling protein (ASIP), partial | E.coli |
| CSB-EP002212HU | Recombinant Human Agouti-signaling protein (ASIP) | E.coli |
ASIP Proteins for Macaca mulatta (Rhesus macaque)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP002212MOW CSB-EP002212MOW CSB-BP002212MOW CSB-MP002212MOW CSB-EP002212MOW-B |
Recombinant Macaca mulatta (Rhesus macaque) Agouti-signaling protein (ASIP) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
ASIP Proteins for Vulpes vulpes (Red fox)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP002212VFW CSB-EP002212VFW CSB-BP002212VFW CSB-MP002212VFW CSB-EP002212VFW-B |
Recombinant Vulpes vulpes Agouti-signaling protein (ASIP) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
ASIP Proteins for Macaca sylvanus (Barbary macaque)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP002212MNE CSB-EP002212MNE CSB-BP002212MNE CSB-MP002212MNE CSB-EP002212MNE-B |
Recombinant Macaca sylvanus Agouti-signaling protein (ASIP) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
ASIP Proteins for Macaca nigra (Celebes black macaque) (Crested black macaque)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP002212MNA CSB-EP002212MNA CSB-BP002212MNA CSB-MP002212MNA CSB-EP002212MNA-B |
Recombinant Macaca nigra Agouti-signaling protein (ASIP) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
ASIP Proteins for Trachypithecus auratus (Javan langur)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP002212TKK CSB-EP002212TKK CSB-BP002212TKK CSB-MP002212TKK CSB-EP002212TKK-B |
Recombinant Trachypithecus auratus Agouti-signaling protein (ASIP) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
ASIP Proteins for Callithrix jacchus (White-tufted-ear marmoset)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP002212CYL CSB-EP002212CYL CSB-BP002212CYL CSB-MP002212CYL CSB-EP002212CYL-B |
Recombinant Callithrix jacchus Agouti-signaling protein (ASIP) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
ASIP Proteins for Callimico goeldii (Goeldi's marmoset)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP002212CYI CSB-EP002212CYI CSB-BP002212CYI CSB-MP002212CYI CSB-EP002212CYI-B |
Recombinant Callimico goeldii Agouti-signaling protein (ASIP) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
ASIP Proteins for Papio anubis (Olive baboon)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP002212ERI CSB-EP002212ERI CSB-BP002212ERI CSB-MP002212ERI CSB-EP002212ERI-B |
Recombinant Papio anubis Agouti-signaling protein (ASIP) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
ASIP Proteins for Cebuella pygmaea (Pygmy marmoset) (Callithrix pygmaea)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP002212DQT CSB-EP002212DQT CSB-BP002212DQT CSB-MP002212DQT CSB-EP002212DQT-B |
Recombinant Cebuella pygmaea Agouti-signaling protein (ASIP) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
ASIP Proteins for Macaca nemestrina (Pig-tailed macaque)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP002212MOX CSB-EP002212MOX CSB-BP002212MOX CSB-MP002212MOX CSB-EP002212MOX-B |
Recombinant Macaca nemestrina Agouti-signaling protein (ASIP) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
ASIP Proteins for Callithrix geoffroyi (Geoffroy's marmoset)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP002212CYK CSB-EP002212CYK CSB-BP002212CYK CSB-MP002212CYK CSB-EP002212CYK-B |
Recombinant Callithrix geoffroyi Agouti-signaling protein (ASIP) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
ASIP Proteins for Leontopithecus chrysomelas (Golden-headed lion tamarin)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP002212LLN CSB-EP002212LLN CSB-BP002212LLN CSB-MP002212LLN CSB-EP002212LLN-B |
Recombinant Leontopithecus chrysomelas Agouti-signaling protein (ASIP) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
ASIP Proteins for Trachypithecus francoisi (Francois's leaf monkey) (Presbytis francoisi)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP002212TOZ CSB-EP002212TOZ CSB-BP002212TOZ CSB-MP002212TOZ CSB-EP002212TOZ-B |
Recombinant Trachypithecus francoisi Agouti-signaling protein (ASIP) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
ASIP Proteins for Leontopithecus rosalia (Golden lion tamarin)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP002212LLO CSB-EP002212LLO CSB-BP002212LLO CSB-MP002212LLO CSB-EP002212LLO-B |
Recombinant Leontopithecus rosalia Agouti-signaling protein (ASIP) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
ASIP Proteins for Macaca nigrescens (Gorontalo macaque) (Macaca nigra nigrescens)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP002212MNB CSB-EP002212MNB CSB-BP002212MNB CSB-MP002212MNB CSB-EP002212MNB-B |
Recombinant Macaca nigrescens Agouti-signaling protein (ASIP) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
ASIP Proteins for Macaca arctoides (Stump-tailed macaque)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP002212MOU CSB-EP002212MOU CSB-BP002212MOU CSB-MP002212MOU CSB-EP002212MOU-B |
Recombinant Macaca arctoides Agouti-signaling protein (ASIP) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
ASIP Proteins for Macaca cyclopis (Taiwan macaque)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP002212MMW CSB-EP002212MMW CSB-BP002212MMW CSB-MP002212MMW CSB-EP002212MMW-B |
Recombinant Macaca cyclopis Agouti-signaling protein (ASIP) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
ASIP Proteins for Macaca silenus (Lion-tailed macaque)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP002212MNC CSB-EP002212MNC CSB-BP002212MNC CSB-MP002212MNC CSB-EP002212MNC-B |
Recombinant Macaca silenus Agouti-signaling protein (ASIP) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
ASIP Proteins for Macaca hecki (Heck's macaque)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP002212MMY CSB-EP002212MMY CSB-BP002212MMY CSB-MP002212MMY CSB-EP002212MMY-B |
Recombinant Macaca hecki Agouti-signaling protein (ASIP) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
ASIP Proteins for Macaca fuscata fuscata (Japanese macaque)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP002212MMX CSB-EP002212MMX CSB-BP002212MMX CSB-MP002212MMX CSB-EP002212MMX-B |
Recombinant Macaca fuscata fuscata Agouti-signaling protein (ASIP) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
ASIP Proteins for Macaca assamensis (Assam macaque) (Assamese macaque)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP002212MMV CSB-EP002212MMV CSB-BP002212MMV CSB-MP002212MMV CSB-EP002212MMV-B |
Recombinant Macaca assamensis Agouti-signaling protein (ASIP) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
ASIP Proteins for Macaca maura (Moor macaque)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP002212MMZ CSB-EP002212MMZ CSB-BP002212MMZ CSB-MP002212MMZ CSB-EP002212MMZ-B |
Recombinant Macaca maura Agouti-signaling protein (ASIP) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
ASIP Proteins for Macaca sinica (Toque macaque) (Toque monkey)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP002212MND CSB-EP002212MND CSB-BP002212MND CSB-MP002212MND CSB-EP002212MND-B |
Recombinant Macaca sinica Agouti-signaling protein (ASIP) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
ASIP Proteins for Chlorocebus aethiops (Green monkey) (Cercopithecus aethiops)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP630272DSU CSB-EP630272DSU CSB-BP630272DSU CSB-MP630272DSU CSB-EP630272DSU-B |
Recombinant Chlorocebus aethiops Agouti-signaling protein (ASIP) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
ASIP Proteins for Gorilla gorilla gorilla (Lowland gorilla)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP631305GGZ CSB-EP631305GGZ CSB-BP631305GGZ CSB-MP631305GGZ CSB-EP631305GGZ-B |
Recombinant Gorilla gorilla gorilla Agouti-signaling protein (ASIP) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
ASIP Proteins for Colobus polykomos (Western black-and-white colobus monkey)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP632343DVI CSB-EP632343DVI CSB-BP632343DVI CSB-MP632343DVI CSB-EP632343DVI-B |
Recombinant Colobus polykomos Agouti-signaling protein (ASIP) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
ASIP Proteins for Pongo pygmaeus (Bornean orangutan)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP632344EXP CSB-EP632344EXP CSB-BP632344EXP CSB-MP632344EXP CSB-EP632344EXP-B |
Recombinant Pongo pygmaeus Agouti-signaling protein (ASIP) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
ASIP Proteins for Macaca radiata (Bonnet macaque)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP633596MOY CSB-EP633596MOY CSB-BP633596MOY CSB-MP633596MOY CSB-EP633596MOY-B |
Recombinant Macaca radiata Agouti-signaling protein (ASIP) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
ASIP Proteins for Erythrocebus patas (Red guenon) (Cercopithecus patas)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP635285EGU CSB-EP635285EGU CSB-BP635285EGU CSB-MP635285EGU CSB-EP635285EGU-B |
Recombinant Erythrocebus patas Agouti-signaling protein (ASIP) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
ASIP Proteins for Semnopithecus entellus (Hanuman langur) (Presbytis entellus)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP636312SEU CSB-EP636312SEU CSB-BP636312SEU CSB-MP636312SEU CSB-EP636312SEU-B |
Recombinant Semnopithecus entellus Agouti-signaling protein (ASIP) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
ASIP Proteins for Pan paniscus (Pygmy chimpanzee) (Bonobo)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP636313EQU CSB-EP636313EQU CSB-BP636313EQU CSB-MP636313EQU CSB-EP636313EQU-B |
Recombinant Pan paniscus Agouti-signaling protein (ASIP) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
ASIP Proteins for Cercopithecus mitis (Blue monkey)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP637353CCAF CSB-EP637353CCAF CSB-BP637353CCAF CSB-MP637353CCAF CSB-EP637353CCAF-B |
Recombinant Cercopithecus mitis Agouti-signaling protein (ASIP) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
ASIP Proteins for Pan troglodytes (Chimpanzee)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP637354EQV CSB-EP637354EQV CSB-BP637354EQV CSB-MP637354EQV CSB-EP637354EQV-B |
Recombinant Pan troglodytes Agouti-signaling protein (ASIP) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
ASIP Proteins for Trachypithecus cristatus (Silvered leaf-monkey) (Presbytis cristata)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP638527TOY CSB-EP638527TOY CSB-BP638527TOY CSB-MP638527TOY CSB-EP638527TOY-B |
Recombinant Trachypithecus cristatus Agouti-signaling protein (ASIP) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
ASIP Proteins for Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP638528MOV CSB-EP638528MOV CSB-BP638528MOV CSB-MP638528MOV CSB-EP638528MOV-B |
Recombinant Macaca fascicularis Agouti-signaling protein (ASIP) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
ASIP Proteins for Bos taurus (Bovine)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP639982BO CSB-MP639982BO CSB-EP639982BO-B |
Recombinant Bovine Agouti-signaling protein (ASIP) | Yeast Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-EP639982BO | Recombinant Bovine Agouti-signaling protein (ASIP) | E.coli |
| CSB-BP639982BO | Recombinant Bovine Agouti-signaling protein (ASIP) | Baculovirus |
ASIP Proteins for Canis familiaris (Dog) (Canis lupus familiaris)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP736035DO CSB-EP736035DO CSB-BP736035DO CSB-MP736035DO CSB-EP736035DO-B |
Recombinant Dog Agouti-signaling protein (ASIP) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
ASIP Proteins for Sus scrofa (Pig)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP758206PI CSB-EP758206PI CSB-BP758206PI CSB-MP758206PI CSB-EP758206PI-B |
Recombinant Pig Agouti-signaling protein (ASIP) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
ASIP Proteins for Felis catus (Cat) (Felis silvestris catus)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP772945CA CSB-EP772945CA CSB-BP772945CA CSB-MP772945CA CSB-EP772945CA-B |
Recombinant Cat Agouti-signaling protein (ASIP) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
ASIP Proteins for Equus caballus (Horse)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP850188HO CSB-EP850188HO CSB-BP850188HO CSB-MP850188HO CSB-EP850188HO-B |
Recombinant Horse Agouti-signaling protein (ASIP) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
ASIP Proteins for Rattus norvegicus (Rat)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP857472RA CSB-EP857472RA CSB-BP857472RA CSB-MP857472RA CSB-EP857472RA-B |
Recombinant Rat Agouti-signaling protein (Asip) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
