AGER

AGER，即高級糖基化終產(chǎn)物特異性受體，別名RAGE，是免疫球蛋白超家族成員，主要表達(dá)于細(xì)胞表面。作為跨膜信號轉(zhuǎn)導(dǎo)受體，AGER與多種配體結(jié)合，通過激活NF-κ-B等信號通路，調(diào)控炎癥細(xì)胞因子釋放，參與細(xì)胞增殖、遷移及炎癥反應(yīng)。在生物學(xué)上，AGER與糖尿病并發(fā)癥、神經(jīng)退行性疾病及癌癥等密切相關(guān)，其表達(dá)受炎癥與氧化應(yīng)激調(diào)控，是評估疾病嚴(yán)重程度及預(yù)后的潛在生物標(biāo)志物。針對AGER的靶向治療，如小分子抑制劑或抗體療法，有望為相關(guān)疾病提供新的治療策略。

熱銷產(chǎn)品

Recombinant Human Advanced glycosylation end product-specific receptor (AGER), partial (CSB-EP001441HU)

驗(yàn)證數(shù)據(jù)

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

AGER Antibody (CSB-PA066696)

驗(yàn)證數(shù)據(jù)

The image is immunohistochemistry of paraffin-embedded Human gastric cancer tissue using CSB-PA066696(AGER Antibody) at dilution 1/70. (Original magnification: ×200)

The image is immunohistochemistry of paraffin-embedded Human liver cancer tissue using CSB-PA066696(AGER Antibody) at dilution 1/70. (Original magnification: ×200)

Gel: 8%SDS-PAGE,Lysate: 40 μg,,Primary antibody: CSB-PA066696(AGER Antibody) at dilution 1/750 dilution,Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution,Exposure time: 2 minutes

AGER Antibody

AGER Protein

AGER ELISA Kit

AGER Antibodies

AGER for Homo sapiens (Human)

產(chǎn)品貨號	產(chǎn)品名稱	種屬反應(yīng)性	應(yīng)用類型
CSB-PA14209B0Rb	AGER Antibody, HRP conjugated	Human	ELISA
CSB-PA14209A0Rb	AGER Antibody	Human	ELISA, IHC, IF
CSB-PA007810	AGER Antibody	Human	WB, IHC, ELISA
CSB-PA066696	AGER Antibody	Human	ELISA,WB,IHC
CSB-PA874417	AGER Antibody	Human	ELISA,WB,IHC

AGER Proteins

AGER Proteins for Mus musculus (Mouse)

產(chǎn)品貨號	產(chǎn)品名稱	來源
CSB-YP001441MO CSB-EP001441MO CSB-BP001441MO CSB-MP001441MO CSB-EP001441MO-B	Recombinant Mouse Advanced glycosylation end product-specific receptor (Ager), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

AGER Proteins for Rattus norvegicus (Rat)

產(chǎn)品貨號	產(chǎn)品名稱	來源
CSB-YP001441RA CSB-EP001441RA CSB-BP001441RA CSB-MP001441RA CSB-EP001441RA-B	Recombinant Rat Advanced glycosylation end product-specific receptor (Ager), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

AGER Proteins for Homo sapiens (Human)

產(chǎn)品貨號	產(chǎn)品名稱	來源
CSB-YP001441HU CSB-EP001441HU CSB-BP001441HU CSB-MP001441HU CSB-EP001441HU-B	Recombinant Human Advanced glycosylation end product-specific receptor (AGER), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-EP001441HU	Recombinant Human Advanced glycosylation end product-specific receptor (AGER), partial	E.coli
CSB-MP001441HU1c7	Recombinant Human Advanced glycosylation end product-specific receptor (AGER), partial	Mammalian cell

AGER Proteins for Bos taurus (Bovine)

產(chǎn)品貨號	產(chǎn)品名稱	來源
CSB-YP001441BO CSB-EP001441BO CSB-BP001441BO CSB-MP001441BO CSB-EP001441BO-B	Recombinant Bovine Advanced glycosylation end product-specific receptor (AGER), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

AGER ELISA Kit

AGER ELISA Kit for Homo sapiens (Human)

產(chǎn)品貨號	產(chǎn)品名稱	樣本類型	靈敏度
CSB-E09354h	Human Receptor for advanced glycation end products, RAGE/AGER ELISA Kit	serum, plasma, tissue homogenates	19.5 pg/mL
CSB-E09354h-IS	Human Receptor for advanced glycation end products, RAGE/AGER ELISA Kit	serum, plasma, tissue homogenates	19.5 pg/mL