ACP5

ACP5，即抗酒石酸酸性磷酸酶5。別名包括TRACP、TRAP，它是一種由第19號染色體上的基因編碼的單一同工酶，是一種結構高度保守的含鐵糖蛋白。ACP5主要存在于巨噬細胞、破骨細胞、Gaucher細胞、紅細胞、血小板、脾臟毛狀細胞以及單核吞噬細胞中，尤其在肺泡巨噬細胞和破骨細胞中含量最豐富。ACP5參與活性氧的生成、正常骨骼發育、成骨細胞調節和巨噬細胞功能，影響一系列途徑，并反映骨骼的吸收和破骨細胞活性。研究表明，RANKL可以通過NFATc1和c-Fos增加ACP5的表達，從而加速破骨細胞的生成。ACP5在預防、監測和治療各種腫瘤以及加速發展人類遺傳疾病的有前景的治療策略中起著至關重要的作用。

熱銷產品

Recombinant Human Tartrate-resistant acid phosphatase type 5 (ACP5) (CSB-YP001178HU)

驗證數據

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

ACP5 Antibody

ACP5 Protein

ACP5 ELISA Kit

ACP5 Antibodies

ACP5 for Homo sapiens (Human)

產品貨號	產品名稱	種屬反應性	應用類型
CSB-PA001178GA01HU	ACP5 Antibody	Human,Mouse,Rat	ELISA,IHC

ACP5 Proteins

ACP5 Proteins for Mus musculus (Mouse)

產品貨號	產品名稱	來源
CSB-YP001178MO CSB-EP001178MO CSB-BP001178MO CSB-MP001178MO CSB-EP001178MO-B	Recombinant Mouse Tartrate-resistant acid phosphatase type 5 (Acp5)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

ACP5 Proteins for Homo sapiens (Human)

產品貨號	產品名稱	來源
CSB-EP001178HU CSB-BP001178HU CSB-EP001178HU-B	Recombinant Human Tartrate-resistant acid phosphatase type 5 (ACP5)	E.coli Baculovirus In Vivo Biotinylation in E.coli
CSB-YP001178HU	Recombinant Human Tartrate-resistant acid phosphatase type 5 (ACP5)	Yeast

ACP5 Proteins for Sus scrofa (Pig)

產品貨號	產品名稱	來源
CSB-YP001178PI CSB-EP001178PI CSB-BP001178PI CSB-MP001178PI CSB-EP001178PI-B	Recombinant Pig Tartrate-resistant acid phosphatase type 5 (ACP5)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

ACP5 Proteins for Oryctolagus cuniculus (Rabbit)

產品貨號	產品名稱	來源
CSB-YP001178RB CSB-EP001178RB CSB-BP001178RB CSB-MP001178RB CSB-EP001178RB-B	Recombinant Rabbit Tartrate-resistant acid phosphatase type 5 (ACP5)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

ACP5 Proteins for Rattus norvegicus (Rat)

產品貨號	產品名稱	來源
CSB-YP001178RA CSB-EP001178RA CSB-BP001178RA CSB-MP001178RA CSB-EP001178RA-B	Recombinant Rat Tartrate-resistant acid phosphatase type 5 (Acp5)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli