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TGFB1

TGFB1,即轉(zhuǎn)化生長因子β1,別名DPD1、LAP等,是一種多功能細胞因子,具有廣泛的生物學功能,包括調(diào)控細胞生長、增殖、分化、凋亡、細胞運動、細胞外基質(zhì)產(chǎn)生、血管生成和細胞免疫反應(yīng)。TGFB1在許多生理和病理過程中發(fā)揮作用,如組織修復(fù)、胚胎發(fā)育、免疫調(diào)節(jié)以及腫瘤發(fā)生。其生物學意義在于通過Smad依賴和非依賴途徑,調(diào)節(jié)多種細胞過程,影響細胞行為和組織穩(wěn)態(tài)。TGFB1的異常信號傳導(dǎo)與多種疾病的發(fā)生發(fā)展有關(guān),包括腫瘤、纖維化疾病、心血管疾病和免疫性疾病等,TGFB1及其信號通路是生物醫(yī)學研究的重要靶點。

熱銷產(chǎn)品

Recombinant Macaca mulatta Transforming growth factor beta (TGFB1) (C33S) (Active) (CSB-MP6752MOW(A4)(M))

驗證數(shù)據(jù)

CSB-MP6752MOW(A4)(M)

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

CSB-MP6752MOW(A4)(M)

Activity
Measured by its binding ability in a functional ELISA. Immobilized Macaca fascicularis ITGAV&ITGB6(CSB-MP6541MOV) at 2 μg/ml can bind Macaca mulatta TGFB1. The EC50 is 8.899-14.82 ng/mL.

CSB-MP6752MOW(A4)(M)

The purity of TGFB1 was greater than 90% as determined by SEC-HPLC

Recombinant Human Transforming growth factor beta-1 proprotein (TGFB1), partial (CSB-EP023446HU1)

驗證數(shù)據(jù)

CSB-EP023446HU1

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

TGFB1 Antibody (CSB-PA07309A0Rb)

驗證數(shù)據(jù)

CSB-PA07309A0Rb

IHC image of CSB-PA07309A0Rb diluted at 1:600 and staining in paraffin-embedded human prostate cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.

CSB-PA07309A0Rb

IHC image of CSB-PA07309A0Rb diluted at 1:600 and staining in paraffin-embedded human liver cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.

Human Transforming Growth factor β1,TGF-β1 ELISA kit (CSB-E04725h)

驗證數(shù)據(jù)

CSB-E04725h 標準曲線

貨號:CSB-E04725h

規(guī)格:96T/48T

靈敏度:0.747 ng/mL

檢測范圍:0.78 ng/mL-50 ng/mL

These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

TGFB1 Antibodies

TGFB1 for Homo sapiens (Human)

TGFB1 for Bovine

TGFB1 for Chicken

TGFB1 for Oncorhynchus mykiss

TGFB1 for Mus musculus (Mouse)

TGFB1 Proteins

TGFB1 Proteins for Rattus norvegicus (Rat)

TGFB1 Proteins for Bos taurus (Bovine)

TGFB1 Proteins for Ovis aries (Sheep)

TGFB1 Proteins for Canis familiaris (Dog) (Canis lupus familiaris)

TGFB1 Proteins for Mus musculus (Mouse)

TGFB1 Proteins for Homo sapiens (Human)

TGFB1 Proteins for Sus scrofa (Pig)

TGFB1 Proteins for Gallus gallus (Chicken)

TGFB1 Proteins for Equus caballus (Horse)

TGFB1 Proteins for Xenopus laevis (African clawed frog)

TGFB1 Proteins for Chlorocebus aethiops (Green monkey) (Cercopithecus aethiops)

TGFB1 Proteins for Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri)

TGFB1 Proteins for Mustela putorius furo (European domestic ferret) (Mustela furo)

TGFB1 Proteins for Cyprinus carpio (Common carp)

TGFB1 ELISA Kit

TGFB1 ELISA Kit for Bos taurus (Bovine)

TGFB1 ELISA Kit for Gallus gallus (Chicken)

TGFB1 ELISA Kit for Canis lupus familiaris (Dog) (Canis familiaris)

TGFB1 ELISA Kit for Equus caballus (Horse)

TGFB1 ELISA Kit for Mus musculus (Mouse)

TGFB1 ELISA Kit for Sus scrofa (Pig)

TGFB1 ELISA Kit for Rattus norvegicus (Rat)

TGFB1 ELISA Kit for Ovis aries (Sheep)

TGFB1 ELISA Kit for Homo sapiens (Human)



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