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  4. SLC39A12 (APL-9796 Biosimilar) Recombinant Monoclonal Antibody

SLC39A12 (APL-9796 Biosimilar) Recombinant Monoclonal Antibody

  • 貨號：
    CSB-RA706511MB1HU
  • 規格：
    ￥83486
  • 其他：

產品詳情

  • Uniprot No.：
  • 基因名：
  • 別名：
    AP13 research-grade biosimilar; APL9796 research-grade biosimilar; APL 9796 research-grade biosimilar; humanized monoclonal antibody directed against human zinc-regulated transporter-like, iron-regulated transporter-like protein 12 research-grade biosimilar ;SLC39A12 antibody; ZIP12 antibody; Zinc transporter ZIP12 antibody; LIV-1 subfamily of ZIP zinc transporter 8 antibody; LZT-Hs8 antibody; Solute carrier family 39 member 12 antibody; Zrt- and Irt-like protein 12 antibody; ZIP-12 antibody
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human SLC39A12 protein
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 克隆類型：
    Monoclonal
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    0.01M PBS，pH7.4
  • 產品提供形式：
    Liquid
  • 應用說明：
    Validation Status
    Application-specific performance (e.g., in flow cytometry, ELISA, IHC or other assay formats) has not yet been experimentally verified by CUSABIO. Users are advised to determine the optimal working conditions empirically in their own assay systems.
    Guaranteed Quality
    ① Antibody purity?> 95% tested by SDS-PAGE.
    ② Endotoxin level < 0.1EU/ug tested by LAL method.
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    3-4 weeks
  • 用途：
    It is a non-therapeutic biosimilar antibody, owning the same variable region from the corresponding approved therapeutic antibody. In conclusion, it is a research-grade biosimilar antibody and expressed in mammalian cell, which can be directly used as positive controls in drug discovery or used for rapid verification of the biological functions of target protein.

產品評價

靶點詳情

  • 功能：
    Acts as a zinc-influx transporter (Potential). May be partly involved in the outbreak of schizophrenia.
  • 基因功能參考文獻：
    1. Data indicate that the zinc transporter ZIP12 (slc39a12) is highly expressed in brain. PMID: 23716681
    2. Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator) PMID: 20379614
    3. Examination of the zinc transporter gene, SLC39A12. PMID: 16311021
    4. Observational study of gene-disease association. (HuGE Navigator) PMID: 16385451
    5. Observational study of gene-disease association. (HuGE Navigator) PMID: 19064571

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  • 亞細胞定位：
    Membrane; Multi-pass membrane protein.
  • 蛋白家族：
    ZIP transporter (TC 2.A.5) family
  • 組織特異性：
    Expressed in brain and eye.
  • 數據庫鏈接：

    HGNC: 20860

    OMIM: 608734

    KEGG: hsa:221074

    STRING: 9606.ENSP00000366586

    UniGene: Hs.350895