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  4. PLD4 (SBI-3150 Biosimilar) Recombinant Monoclonal Antibody

PLD4 (SBI-3150 Biosimilar) Recombinant Monoclonal Antibody

  • 貨號：
    CSB-RA839298MB1HU
  • 規格：
    ￥83486
  • 其他：

產品詳情

  • Uniprot No.：
  • 基因名：
  • 別名：
    AK1910 research-grade biosimilar; AK 1910 research-grade biosimilar; SBI3150 research-grade biosimilar; SBI 3150 research-grade biosimilar ;PLD4 antibody; C14orf175 antibody; UNQ2488/PRO5775 antibody; 5'-3' exonuclease PLD4 antibody; EC 3.1.16.1 antibody; (S,S-bis(monoacylglycerophosphate synthase PLD4 antibody; EC 3.1.4.- antibody; Phospholipase D family member 4 antibody; Phospholipase D4 antibody
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human PLD4 protein
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 克隆類型：
    Monoclonal
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    0.01M PBS，pH7.4
  • 產品提供形式：
    Liquid
  • 應用說明：
    Validation Status
    Application-specific performance (e.g., in flow cytometry, ELISA, IHC or other assay formats) has not yet been experimentally verified by CUSABIO. Users are advised to determine the optimal working conditions empirically in their own assay systems.
    Guaranteed Quality
    ① Antibody purity?> 95% tested by SDS-PAGE.
    ② Endotoxin level < 0.1EU/ug tested by LAL method.
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    3-4 weeks
  • 用途：
    It is a non-therapeutic biosimilar antibody, owning the same variable region from the corresponding approved therapeutic antibody. In conclusion, it is a research-grade biosimilar antibody and expressed in mammalian cell, which can be directly used as positive controls in drug discovery or used for rapid verification of the biological functions of target protein.

產品評價

靶點詳情

  • 功能：
    5'->3' DNA exonuclease which digests single-stranded DNA (ssDNA). Regulates inflammatory cytokine responses via the degradation of nucleic acids, by reducing the concentration of ssDNA able to stimulate TLR9, a nucleotide-sensing receptor. Involved in phagocytosis of activated microglia.
  • 基因功能參考文獻：
    1. PLD4 expression in colon cancer tissues PMID: 27840999
    2. We determined that PLD4 is a novel susceptibility gene for sysetmic sclerosis in Japanese, thus confirming the involvement of PLD4 in autoimmunity. PMID: 23124809
  • 亞細胞定位：
    Endoplasmic reticulum membrane; Single-pass type II membrane protein. Golgi apparatus, trans-Golgi network membrane; Single-pass type II membrane protein. Nucleus. Early endosome. Cytoplasmic vesicle, phagosome.
  • 蛋白家族：
    Phospholipase D family
  • 數據庫鏈接：

    HGNC: 23792

    KEGG: hsa:122618

    STRING: 9606.ENSP00000376372

    UniGene: Hs.407101