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  4. LRRC15 (Samrotamab Biosimilar) Recombinant Monoclonal Antibody

LRRC15 (Samrotamab Biosimilar) Recombinant Monoclonal Antibody

  • 貨號：
    CSB-RA819484MB1HU
  • 規格：
    ￥83486
  • 其他：

產品詳情

  • Uniprot No.：
  • 基因名：
  • 別名：
    Leucine-rich repeat-containing protein 15；Leucine-rich repeat protein induced by beta-amyloid homolog；hLib , LRRC15, LIB
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human LRRC15 protein
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 克隆類型：
    Monoclonal
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    0.01M PBS，pH7.4
  • 產品提供形式：
    Liquid
  • 應用說明：
    Validation Status
    Application-specific performance (e.g., in flow cytometry, ELISA, IHC or other assay formats) has not yet been experimentally verified by CUSABIO. Users are advised to determine the optimal working conditions empirically in their own assay systems.
    Guaranteed Quality
    ① Antibody purity?> 95% tested by SDS-PAGE.
    ② Endotoxin level < 0.1EU/ug tested by LAL method.
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    In stock
  • 用途：
    It is a non-therapeutic biosimilar antibody, owning the same variable region from the corresponding approved therapeutic antibody. In conclusion, it is a research-grade biosimilar antibody and expressed in mammalian cell, which can be directly used as positive controls in drug discovery or used for rapid verification of the biological functions of target protein.

產品評價

靶點詳情

  • 基因功能參考文獻：
    1. LRRC15 expression is significantly upregulated in human masticatory mucosa during wound healing PMID: 28005267
    2. Lib may contribute to regulation of cell-matrix adhesion interactions with respect to astrocyte recruitment around senile plaques in Alzheimer's disease brain PMID: 16098915
    3. Tumor antigen LRRC15 impedes adenoviral infection: implications for virus-based cancer therapy are presented. PMID: 18385238
    4. LRRC15 is induced by EWS-WT1(+KTS) in the tumor DSRCT and may play a role in cellular invasion. PMID: 12923058
  • 亞細胞定位：
    Membrane; Single-pass type I membrane protein.
  • 組織特異性：
    Brain and placenta.
  • 數據庫鏈接：

    HGNC: 20818

    KEGG: hsa:131578

    STRING: 9606.ENSP00000389128

    UniGene: Hs.288467