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  4. Recombinant Rabbit Stromelysin-1 (MMP3)

Recombinant Rabbit Stromelysin-1 (MMP3)

  • 中文名稱：
    小圓錐花果MMP3重組蛋白
  • 貨號：
    CSB-YP014676RB
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    小圓錐花果MMP3重組蛋白
  • 貨號：
    CSB-EP014676RB
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    小圓錐花果MMP3重組蛋白
  • 貨號：
    CSB-EP014676RB-B
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    小圓錐花果MMP3重組蛋白
  • 貨號：
    CSB-BP014676RB
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    小圓錐花果MMP3重組蛋白
  • 貨號：
    CSB-MP014676RB
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 別名：
    MMP3; Stromelysin-1; SL-1; EC 3.4.24.17; Matrix metalloproteinase-3; MMP-3; Transin-1
  • 種屬：
    Oryctolagus cuniculus (Rabbit)
  • 蛋白長度：
    Full length protein
  • 表達區域：
    101-478
  • 氨基酸序列
    FSTFPGTPKW TKTHLTYRIV NYTPDLPRDA VDAAIEKALK VWEEVTPLTF SRKYEGEADI MISFGVREHG DFIPFDGPGN VLAHAYAPGP GINGDAHFDD DEQWTKDTTG TNLFLVAAHE LGHSLGLFHS ANPEALMYPV YNAFTDLARF RLSQDDVDGI QSLYGPAPAS PDNSGVPMEP VPPGSGTPVM CDPDLSFDAI STLRGEILFF KDRYFWRKSL RILEPEFHLI SSFWPSLPSA VDAAYEVISR DTVFIFKGTQ FWAIRGNEVQ AGYPRSIHTL GFPSTIRKID AAISDKERKK TYFFVEDKYW RFDEKRQSLE PGFPRHIAED FPGINPKIDA VFEAFGFFYF FSGSSQSEFD PNAKKVTHVL KSNSWFQC
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Can degrade fibronectin, laminin, gelatins of type I, III, IV, and V; collagens III, IV, X, and IX, and cartilage proteoglycans. Activates procollagenase.
  • 基因功能參考文獻：
    1. Compromised autophagy may be related to the osteoarthritis progression; JNK and p38 MAPKs up-regulate MMP3 and down-regulate autophagy. PMID: 26873249
    2. the total content and active forms of matrix metalloproteinases (MMPs)-1, -3, and -13 was measured to assess the potential role of the mechanical environment in regulation of matrix turnover by ligament fibroblasts. PMID: 23879595
    3. chitosan-pDNA nanoparticles encoding shRNA targeting MMP-3 and -13 had great potential in silencing the dedifferentiation-related genes for regenerating prolonged and endurable cartilage. PMID: 23520014
    4. Ulinastatin effectively inhibited the increased expression of MMP-2, MMP-3, and iNOS in degenerated NP cells induced by IL-1beta in vitro. PMID: 22853554
    5. Exposure to long periods of light irrespective of its characteristics leads to the increased expression of some matrix metalloprpteases. PMID: 20238014
    6. Tongxinluo can inhibit the expression of MMP-3 and 9 and increase the expression of PPARgamma in atherosclerotic rabbits. PMID: 19778818

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  • 亞細胞定位：
    Secreted, extracellular space, extracellular matrix.
  • 蛋白家族：
    Peptidase M10A family
  • 數據庫鏈接：


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