Recombinant Pig Low-density lipoprotein receptor (LDLR), partial

中文名稱：

野豬LDLR重組蛋白
貨號(hào)：

CSB-YP636741PI
規(guī)格：
來(lái)源：

Yeast
其他：

中文名稱：

野豬LDLR重組蛋白
貨號(hào)：

CSB-EP636741PI
規(guī)格：
來(lái)源：

E.coli
其他：

中文名稱：

野豬LDLR重組蛋白
貨號(hào)：

CSB-EP636741PI-B
規(guī)格：
來(lái)源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

野豬LDLR重組蛋白
貨號(hào)：

CSB-BP636741PI
規(guī)格：
來(lái)源：

Baculovirus
其他：

中文名稱：

野豬LDLR重組蛋白
貨號(hào)：

CSB-MP636741PI
規(guī)格：
來(lái)源：

Mammalian cell
其他：

產(chǎn)品詳情
產(chǎn)品評(píng)價(jià)
靶點(diǎn)詳情

產(chǎn)品詳情

純度：

>85% (SDS-PAGE)
基因名：

LDLR
Uniprot No.：

Q28832
別名：

LDLR; Low-density lipoprotein receptor; LDL receptor; Fragment
種屬：

Sus scrofa (Pig)
蛋白長(zhǎng)度：

Partial
蛋白標(biāo)簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產(chǎn)品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復(fù)溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲(chǔ)存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質(zhì)期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項(xiàng)：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

功能：

Binds LDL, the major cholesterol-carrying lipoprotein of plasma, and transports it into cells by endocytosis. In order to be internalized, the receptor-ligand complexes must first cluster into clathrin-coated pits.
基因功能參考文獻(xiàn)：
1. The LDLR gene should be a candidate causative gene for LDL-cholesterol and total cholesterol in pigs, but heterogeneity exists in different populations. PMID: 24954195
2. KLF13 and SREBP-Sp1 activation interact to regulate low density lipoprotein receptor promoter function PMID: 16303770
3. found association between genotypes for LDLR and APOB polymorphisms and serum lipid levels, but none of them seem to be the causal mutation but probably represent closely linked polymorphisms PMID: 19544207
相關(guān)疾病：

Defects in LDLR are the cause of familial hypercholesterolemia (FH).
亞細(xì)胞定位：

Cell membrane; Single-pass type I membrane protein. Membrane, clathrin-coated pit. Golgi apparatus. Early endosome. Late endosome. Lysosome.
蛋白家族：

LDLR family
數(shù)據(jù)庫(kù)鏈接：

KEGG: ssc:396801

STRING: 9823.ENSSSCP00000030589

UniGene: Ssc.54157