Recombinant Mouse Glycoprotein hormone beta-5 (Gphb5)

中文名稱：

小鼠Gphb5重組蛋白
貨號：

CSB-YP767382MO
規(guī)格：
來源：

Yeast
其他：

中文名稱：

小鼠Gphb5重組蛋白
貨號：

CSB-EP767382MO-B
規(guī)格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

小鼠Gphb5重組蛋白
貨號：

CSB-BP767382MO
規(guī)格：
來源：

Baculovirus
其他：

中文名稱：

小鼠Gphb5重組蛋白
貨號：

CSB-MP767382MO
規(guī)格：
來源：

Mammalian cell
其他：

產(chǎn)品詳情
產(chǎn)品評價
相關(guān)產(chǎn)品
靶點詳情

產(chǎn)品詳情

純度：

>85% (SDS-PAGE)
基因名：

Gphb5
Uniprot No.：

Q812B2
別名：

Gphb5; Gpb5; Zlut1; Glycoprotein hormone beta-5; Thyrostimulin subunit beta
種屬：

Mus musculus (Mouse)
蛋白長度：

Full Length of Mature Protein
表達(dá)區(qū)域：

25-130
氨基酸序列

SSSGNL HTFVGCAVRE FTFMAKKPGC RGLRITTDAC WGRCETWEKP ILEPPYIEAY HRVCTYNETR QVTVKLPNCA PGVDPFYTYP MAVRCDCGAC STATTECETI
蛋白標(biāo)簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產(chǎn)品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復(fù)溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質(zhì)期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產(chǎn)品評價

靶點詳情

功能：

Functions as a heterodimeric glycoprotein hormone with GPHA2 able to bind and activate the thyroid-stimulating hormone receptor (TSHR), leading to increased cAMP production. Plays a central role in controlling thyroid cell metabolism.
基因功能參考文獻(xiàn)：
1. lacking GPB5 during acute illness does not affect the LPS-induced decrease of serum thyroid hormones PMID: 25117405
2. Results demonstrate in vivo regulation of central GPB5 transcription during acute illness. PMID: 21314737
3. when GPB5-TG mice are challenged with a high-fat diet, they gain significantly less weight and body fat than their WT littermates PMID: 15699348
亞細(xì)胞定位：

Secreted.
蛋白家族：

Glycoprotein hormones subunit beta family
組織特異性：

Expressed in the anterior lobe of pituitary.
數(shù)據(jù)庫鏈接：

KEGG: mmu:217674

STRING: 10090.ENSMUSP00000061488

UniGene: Mm.252250