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  4. Recombinant Human herpesvirus 1 Tripartite terminase subunit 3 (TRM3), partial

Recombinant Human herpesvirus 1 Tripartite terminase subunit 3 (TRM3), partial

  • 中文名稱：
    Recombinant Human herpesvirus 1 Tripartite terminase subunit 3(TRM3),partial
  • 貨號：
    CSB-YP366131HWY
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    Recombinant Human herpesvirus 1 Tripartite terminase subunit 3(TRM3),partial
  • 貨號：
    CSB-EP366131HWY
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    Recombinant Human herpesvirus 1 Tripartite terminase subunit 3(TRM3),partial
  • 貨號：
    CSB-EP366131HWY-B
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    Recombinant Human herpesvirus 1 Tripartite terminase subunit 3(TRM3),partial
  • 貨號：
    CSB-BP366131HWY
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    Recombinant Human herpesvirus 1 Tripartite terminase subunit 3(TRM3),partial
  • 貨號：
    CSB-MP366131HWY
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    TRM3
  • Uniprot No.：
  • 別名：
    TRM3; UL15; Tripartite terminase subunit 3; EC 3.1.-.-; Terminase large subunit
  • 種屬：
    Human herpesvirus 1 (strain 17) (HHV-1) (Human herpes simplex virus 1)
  • 蛋白長度：
    Partial
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Component of the molecular motor that translocates viral genomic DNA in empty capsid during DNA packaging. Forms a tripartite terminase complex together with TRM1 and TRM2 in the host cytoplasm. Once the complex reaches the host nucleus, it interacts with the capsid portal vertex. This portal forms a ring in which genomic DNA is translocated into the capsid. TRM3 carries an RNase H-like nuclease activity that plays an important role for the cleavage of concatemeric viral DNA into unit length genomes.
  • 基因功能參考文獻：
    1. X-ray structure of the C-terminal domain of the terminase large-subunit pUL15 (pUL15C) from HSV-1 PMID: 23596306
    2. These data suggest that pU(L)15 plays an essential role in DNA translocation into the capsid and indicate that this function is separable from its role in DNA cleavage. PMID: 21880766
    3. There is an association between the UL28 and UL15 proteins that is essential for DNA cleavage and packaging in HSV-1. PMID: 17035316
  • 亞細胞定位：
    Host nucleus.
  • 蛋白家族：
    Herpesviridae TRM3 protein family
  • 數據庫鏈接：

    KEGG: vg:2703385