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  4. Recombinant Human Ras-related protein Rab-15 (RAB15)

Recombinant Human Ras-related protein Rab-15 (RAB15)

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  • 中文名稱：
    Recombinant Human Ras-related protein Rab-15 (RAB15)
  • 品名簡稱：
    Recombinant Human RAB15 protein
  • 貨號：
    CSB-EP019163HU
  • 說明書：
  • 規(guī)格：
    ￥1536
  • 圖片：
    • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
  • 其他：

產(chǎn)品詳情

  • 純度：
    Greater than 95% as determined by SDS-PAGE.
  • 生物活性：
    Not Test
  • 基因名：
    RAB15
  • Uniprot No.：
  • 種屬：
    Homo sapiens (Human)
  • 蛋白長度：
    Full Length
  • 來源：
    E.coli
  • 分子量：
    25.5 kDa
  • 表達區(qū)域：
    1-212aa
  • 氨基酸序列
    MAKQYDVLFRLLLIGDSGVGKTCLLCRFTDNEFHSSHISTIGVDFKMKTIEVDGIKVRIQIWDTAGQERYQTITKQYYRRAQGIFLVYDISSERSYQHIMKWVSDVDEYAPEGVQKILIGNKADEEQKRQVGREQGQQLAKEYGMDFYETSACTNLNIKESFTRLTELVLQAHRKELEGLRMRASNELALAELEEEEGKPEGPANSSKTCWC
    Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
    If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
  • 蛋白標簽：
    C-terminal 6xHis-tagged
  • 產(chǎn)品提供形式：
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 緩沖液：
    If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    3-7 business days
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.
  • Datasheet & COA：
    Please contact us to get it.

產(chǎn)品評價

靶點詳情

  • 功能：
    May act in concert with RAB3A in regulating aspects of synaptic vesicle membrane flow within the nerve terminal.
  • 基因功能參考文獻：
    1. identified 4 Rab15 isoforms, Rab15CN, Rab15AN1, Rab15AN2 and Rab15AN3 in neuroblastoma cells and demonstrated that Rab15 isoform balance was significantly decreased in spheres of neuroblastoma cells; study suggests Rab15 alternative splicing may serve as a biomarker to discriminate tumor-initiating cells (TICs) from non-TICs in neuroblastoma PMID: 22427180
    2. Rab15 expression correlates with retinoic acid-induced differentiation of neuroblastoma cells PMID: 21491086
    3. Observational study of gene-disease association. (HuGE Navigator) PMID: 19913121
    4. Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator) PMID: 20628086
    5. Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator) PMID: 20379614
    6. Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator) PMID: 19170196
    7. Rab15 effector protein is a binding partner for Rab15-GTP. PMID: 16195351
    8. Observational study of gene-disease association. (HuGE Navigator) PMID: 19773279
    9. Observational study of gene-disease association. (HuGE Navigator) PMID: 19692168
    10. Observational study of gene-disease association. (HuGE Navigator) PMID: 19625176
    11. Observational study of gene-disease association. (HuGE Navigator) PMID: 18676680

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  • 亞細胞定位：
    Cell membrane; Lipid-anchor; Cytoplasmic side.
  • 蛋白家族：
    Small GTPase superfamily, Rab family
  • 數(shù)據(jù)庫鏈接：

    HGNC: 20150

    KEGG: hsa:376267

    UniGene: Hs.512492