Recombinant Human Endogenous retrovirus group K member 6 Env polyprotein (ERVK-6), partial

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中文名稱：

人ERVK-6重組蛋白
品名簡稱：

Recombinant Human ERVK-6 protein, partial
貨號：

CSB-EP724336HUa0
說明書：

MSDS Datasheet
規格：

￥1836
圖片：
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
其他：

產品詳情
產品評價
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靶點詳情

產品詳情

純度：

Greater than 85% as determined by SDS-PAGE.
基因名：

ERVK-6
Uniprot No.：

Q69384
別名：

ERVK-6; ERVK6Endogenous retrovirus group K member 6 Env polyprotein; EnvK2 protein; Envelope polyprotein; HERV-K(C7) envelope protein; HERV-K(HML-2.HOM) envelope protein; HERV-K108 envelope protein; HERV-K_7p22.1 provirus ancestral Env polyprotein) [Cleaved into: Surface protein; SU); Transmembrane protein; TM)]
種屬：

Homo sapiens (Human)
蛋白長度：

Extracellular Domain
來源：

E.coli
分子量：

65.5 kDa
表達區域：

90-632aa
氨基酸序列

LPMPAGAAAANYTYWAYVPFPPLIRAVTWMDNPTEVYVNDSVWVPGPIDDRCPAKPEEEGMMINISIGYHYPPICLGRAPGCLMPAVQNWLVEVPTVSPICRFTYHMVSGMSLRPRVNYLQDFSYQRSLKFRPKGKPCPKEIPKESKNTEVLVWEECVANSAVILQNNEFGTIIDWAPRGQFYHNCSGQTQSCPSAQVSPAVDSDLTESLDKHKHKKLQSFYPWEWGEKGISTPRPKIVSPVSGPEHPELWRLTVASHHIRIWSGNQTLETRDRKPFYTIDLNSSLTVPLQSCVKPPYMLVVGNIVIKPDSQTITCENCRLLTCIDSTFNWQHRILLVRAREGVWIPVSMDRPWEASPSVHILTEVLKGVLNRSKRFIFTLIAVIMGLIAVTATAAVAGVALHSSVQSVNFVNDWQKNSTRLWNSQSSIDQKLANQINDLRQTVIWMGDRLMSLEHRFQLQCDWNTSDFCITPQIYNESEHHWDMVRRHLQGREDNLTLDISKLKEQIFEASKAHLNLVPGTEAIAGVADGLANLNPVTWVKT
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
蛋白標簽：

N-terminal 6xHis-tagged
產品提供形式：

Liquid or Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
緩沖液：

Tris-based buffer,50% glycerol
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

3-7 business days
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
產品描述：

內源性逆轉錄病毒K群成員6(ERVK-6)是一種內源性逆轉錄病毒。內源性逆轉錄病毒是一類曾經插入宿主基因組的病毒，其遺傳物質以RNA為基礎，但可以逆轉錄成DNA并插入宿主基因組。

華美生物的重組人ERVK-6蛋白是通過大腸桿菌表達系統表達的，包含ERVK-6的胞外結構域，表達區域為90-632aa。該產品可用于體外實驗、蛋白相互作用研究和功能性實驗。作為研究工具，它為科學家提供了一個有力的資源，用于深入了解ERVK6的生物學功能和潛在作用。

通過研究EVK-6蛋白，可以深入了解內源性逆轉錄病毒在宿主基因組中的角色。這一研究有助于揭示內源性逆轉錄病毒與宿主細胞之間相互作用的機制，以及它們在生理和病理條件下的潛在影響。
Datasheet & COA：

Please contact us to get it.

產品評價

靶點詳情

功能：

Retroviral envelope proteins mediate receptor recognition and membrane fusion during early infection. Endogenous envelope proteins may have kept, lost or modified their original function during evolution. This endogenous envelope protein has lost its original fusogenic properties.; SU mediates receptor recognition.; TM anchors the envelope heterodimer to the viral membrane through one transmembrane domain. The other hydrophobic domain, called fusion peptide, mediates fusion of the viral membrane with the target cell membrane.
亞細胞定位：

[Transmembrane protein]: Cell membrane; Single-pass type I membrane protein.; [Surface protein]: Cell membrane; Peripheral membrane protein.; [Endogenous retrovirus group K member 6 Env polyprotein]: Virion.
蛋白家族：

Beta type-B retroviral envelope protein family, HERV class-II K(HML-2) env subfamily
組織特異性：

Expressed in testis, and peripheral blood lymphocytes.
數據庫鏈接：

HGNC: 13915

OMIM: 605626