Recombinant Human Autophagy-related protein 101 (ATG101)

中文名稱：

Recombinant Human Autophagy-related protein 101(ATG101)
貨號：

CSB-YP883590HU
規(guī)格：
來源：

Yeast
其他：

中文名稱：

Recombinant Human Autophagy-related protein 101(ATG101)
貨號：

CSB-EP883590HU
規(guī)格：
來源：

E.coli
其他：

中文名稱：

Recombinant Human Autophagy-related protein 101(ATG101)
貨號：

CSB-EP883590HU-B
規(guī)格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

Recombinant Human Autophagy-related protein 101(ATG101)
貨號：

CSB-BP883590HU
規(guī)格：
來源：

Baculovirus
其他：

中文名稱：

Recombinant Human Autophagy-related protein 101(ATG101)
貨號：

CSB-MP883590HU
規(guī)格：
來源：

Mammalian cell
其他：

產(chǎn)品詳情
產(chǎn)品評價
相關(guān)產(chǎn)品
靶點詳情

產(chǎn)品詳情

純度：

>85% (SDS-PAGE)
基因名：

ATG101
Uniprot No.：

Q9BSB4
別名：

ATG101; Atg13-interacting protein; ATGA1_HUMAN; Autophagy-related protein 101; C12orf44; Chromosome 12 open reading frame 44; FLJ11773; OTTHUMP00000241687; OTTHUMP00000241688; OTTHUMP00000241689
種屬：

Homo sapiens (Human)
蛋白長度：

full length protein
表達區(qū)域：

1-218
氨基酸序列

MNCRSEVLEV SVEGRQVEEA MLAVLHTVLL HRSTGKFHYK KEGTYSIGTV GTQDVDCDFI DFTYVRVSSE ELDRALRKVV GEFKDALRNS GGDGLGQMSL EFYQKKKSRW PFSDECIPWE VWTVKVHVVA LATEQERQIC REKVGEKLCE KIINIVEVMN RHEYLPKMPT QSEVDNVFDT GLRDVQPYLY KISFQITDAL GTSVTTTMRR LIKDTLAL
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產(chǎn)品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質(zhì)期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產(chǎn)品評價

靶點詳情

功能：

Autophagy factor required for autophagosome formation. Stabilizes ATG13, protecting it from proteasomal degradation.
基因功能參考文獻：
1. Structure of the human Atg13-Atg101 HORMA heterodimer in the ULK1 complex that controls autophagy has been described. PMID: 26299944
2. Data indicate mitogen lacritin stimulates FOXO3-ATG101 and FOXO1-ATG7 autophagic coupling and restores metabolic homeostasis. PMID: 23640897
3. The identification of the novel protein, Atg101, and the validation of Atg13 and Atg101 as ULK1-interacting proteins, suggests an Atg1 complex is involved in the induction of macroautophagy in mammalian cells. PMID: 19287211
4. These data suggest that Atg101 is a novel Atg protein that functions together with ULK, Atg13 and FIP200. PMID: 19597335
亞細胞定位：

Cytoplasm. Preautophagosomal structure.
蛋白家族：

ATG101 family
數(shù)據(jù)庫鏈接：

HGNC: 25679

OMIM: 615089

KEGG: hsa:60673

STRING: 9606.ENSP00000338990

UniGene: Hs.9911