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Recombinant Helicobacter pylori Bacterial non-heme ferritin (ftnA)

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  • 中文名稱:
    幽門螺旋桿菌ftnA重組蛋白
  • 品名簡稱:
    Recombinant Helicobacter pylori ftnA protein
  • 貨號:
    CSB-BP009053HUV
  • 說明書:
  • 規格:
    ¥3168
  • 圖片:
    • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
  • 其他:

產品詳情

  • 純度:
    Greater than 85% as determined by SDS-PAGE.
  • 基因名:
  • Uniprot No.:
  • 別名:
    ftnA; pfr; HP_0653Bacterial non-heme ferritin; EC 1.16.3.2
  • 種屬:
    Helicobacter pylori (strain ATCC 700392 / 26695) (Campylobacter pylori)
  • 蛋白長度:
    Full Length
  • 來源:
    Baculovirus
  • 分子量:
    21.8 kDa
  • 表達區域:
    1-167aa
  • 氨基酸序列
    MLSKDIIKLLNEQVNKEMNSSNLYMSMSSWCYTHSLDGAGLFLFDHAAEEYEHAKKLIVFLNENNVPVQLTSISAPEHKFEGLTQIFQKAYEHEQHISESINNIVDHAIKGKDHATFNFLQWYVSEQHEEEVLFKDILDKIELIGNENHGLYLADQYVKGIAKSRKS
    Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
    If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
  • 蛋白標簽:
    N-terminal 10xHis-tagged
  • 產品提供形式:
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 緩沖液:
    Tris-based buffer,50% glycerol
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    3-7 business days
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • 產品描述:

    The production of this Recombinant H. pylori C17orf99 protein began at the genetic level, where the coding sequence for the C17orf99 protein was first isolated and cloned into an expression plasmid vector. Recombinant DNA technology was used in the process. Next step was cloning. The expression vector must be introduced into the host cell (Baculovirus) so that the cells could be cultured and expressed the desired ftnA protein. And we finally got the recombinant ftnA protein with the purity of 85%+ determined by SDS-PAGE.

    Ferritin A (FtnA), a major iron storage protein in E. coli, can scavenge the iron released from the disrupted iron–sulfur clusters and alleviates the iron-mediated production of hydroxyl free radicals in the presence of hydrogen peroxide. Ferritin minerals are nutritive iron concentrates that slowly release the iron for use in the synthesis of new iron centers for protein catalysts as in heme, iron–sulfur clusters, or iron bound entirely by protein in amino acid side chains (“non-heme iron”). Iron-containing proteins are key to electron transfer chains in respiration (heme proteins) and photosynthesis (iron–sulfur proteins) and play important roles in hydroxylation reactions. The iron stored in FtnA can be retrieved by IscA for the iron–sulfur cluster assembly in IscU in the presence of the thioredoxin reductase system. The physiological roles of ferritins in cellular response to oxidative stresses and in repair of the disrupted iron–sulfur clusters have been identified. Increasing evidence indicated that ferritins, a large family of iron-storage proteins found in bacteria and mammalian cells may have an important role in cellular defense against oxidative stresses.

  • Datasheet & COA:
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Iron-storage protein.
  • 亞細胞定位:
    Cytoplasm.
  • 蛋白家族:
    Ferritin family, Prokaryotic subfamily
  • 數據庫鏈接:


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