Recombinant Drosophila melanogaster Origin recognition complex subunit 5 (Orc5)

中文名稱：

黑腹果蠅Orc5重組蛋白
貨號(hào)：

CSB-YP636547DLU
規(guī)格：
來(lái)源：

Yeast
其他：

中文名稱：

黑腹果蠅Orc5重組蛋白
貨號(hào)：

CSB-EP636547DLU
規(guī)格：
來(lái)源：

E.coli
其他：

中文名稱：

黑腹果蠅Orc5重組蛋白
貨號(hào)：

CSB-EP636547DLU-B
規(guī)格：
來(lái)源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

黑腹果蠅Orc5重組蛋白
貨號(hào)：

CSB-BP636547DLU
規(guī)格：
來(lái)源：

Baculovirus
其他：

中文名稱：

黑腹果蠅Orc5重組蛋白
貨號(hào)：

CSB-MP636547DLU
規(guī)格：
來(lái)源：

Mammalian cell
其他：

產(chǎn)品詳情
產(chǎn)品評(píng)價(jià)
靶點(diǎn)詳情

產(chǎn)品詳情

純度：

>85% (SDS-PAGE)
基因名：

Orc5
Uniprot No.：

Q24169
別名：

Orc5; CG7833; Origin recognition complex subunit 5
種屬：

Drosophila melanogaster (Fruit fly)
蛋白長(zhǎng)度：

full length protein
表達(dá)區(qū)域：

1-460
氨基酸序列

MEAICSSLEP LFPCREAAIE TLGELIGDSS ETYPSAIYLF GHSGTGKTAL TRAFLKECGK RQNVRTAHLN AIECYTTKIM LEILLDSLAP DQGDALKVDN MLDFVEQLRR QAATRVEDQG FLIAVDNAER LRDMDANVLP VLLRLQELTN LNLCVILLSQ LPFEKFYNKT GLSEIVCLHL AQYNKAETQR ILGSDFQQVR NQLLEQFAQD KKRLEICQEA VTEDFYNNYL NLFLSVFYKA CRDVPELQLT ARKCLSTYLE PVLDGTVDAT DISRLWRHIA GPLRSALTQI YMRIEKPAEE VEDFTAIEDQ SVRKLAQSLE LPYYAKFLLI AAFLASHNAA KQDKRLFVKH HGKQRKRMQT VNARAKTTEK MSTTLGPKSF SIDRLLAIFY AILEEKVGLT CNLLSQISTL VHLNLLSFVS GEQNIMEGSA RLQCTIGLEF VLQIGKVVGF NVRQYLCDFM
蛋白標(biāo)簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產(chǎn)品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復(fù)溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲(chǔ)存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質(zhì)期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項(xiàng)：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

功能：

Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.
基因功能參考文獻(xiàn)：
1. Data propose that the interaction between ORC5 and dE2F1 may reflect a feedback mechanism between replication initiation proteins and dE2F1 that ensures that proliferating cells maintain a robust level of replication proteins for the next cell cycle. PMID: 22972499
2. ATP-dependent conformational changes observed in ORC5 derive from reorientation of the domains PMID: 16829958
亞細(xì)胞定位：

Nucleus.
蛋白家族：

ORC5 family
數(shù)據(jù)庫(kù)鏈接：

KEGG: dme:Dmel_CG7833

STRING: 7227.FBpp0080120

UniGene: Dm.30749