Recombinant Dog Somatostatin receptor type 2 (SSTR2), partial

中文名稱：

熟悉的犬SSTR2重組蛋白
貨號：

CSB-YP676611DO1
規(guī)格：
來源：

Yeast
其他：

中文名稱：

熟悉的犬SSTR2重組蛋白
貨號：

CSB-EP676611DO1
規(guī)格：
來源：

E.coli
其他：

中文名稱：

熟悉的犬SSTR2重組蛋白
貨號：

CSB-EP676611DO1-B
規(guī)格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

熟悉的犬SSTR2重組蛋白
貨號：

CSB-BP676611DO1
規(guī)格：
來源：

Baculovirus
其他：

中文名稱：

熟悉的犬SSTR2重組蛋白
貨號：

CSB-MP676611DO1
規(guī)格：
來源：

Mammalian cell
其他：

產(chǎn)品詳情
產(chǎn)品評價
相關(guān)產(chǎn)品
靶點詳情

產(chǎn)品詳情

純度：

>85% (SDS-PAGE)
基因名：

SSTR2
Uniprot No.：

Q49LX6
別名：

SSTR2; Somatostatin receptor type 2; SS-2-R; SS2-R; SS2R
種屬：

Canis familiaris (Dog) (Canis lupus familiaris)
蛋白長度：

Partial
蛋白標(biāo)簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產(chǎn)品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復(fù)溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質(zhì)期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產(chǎn)品評價

靶點詳情

功能：

Receptor for somatostatin-14 and -28. This receptor is coupled via pertussis toxin sensitive G proteins to inhibition of adenylyl cyclase. In addition it stimulates phosphotyrosine phosphatase and PLC via pertussis toxin insensitive as well as sensitive G proteins. Inhibits calcium entry by suppressing voltage-dependent calcium channels. Acts as the functionally dominant somatostatin receptor in pancreatic alpha- and beta-cells where it mediates the inhibitory effect of somatostatin-14 on hormone secretion. Inhibits cell growth through enhancement of MAPK1 and MAPK2 phosphorylation and subsequent up-regulation of CDKN1B. Stimulates neuronal migration and axon outgrowth and may participate in neuron development and maturation during brain development. Mediates negative regulation of insulin receptor signaling through PTPN6. Inactivates SSTR3 receptor function following heterodimerization.
基因功能參考文獻(xiàn)：
1. The expression of somatostatin receptor 2 was was negatively correlated with malignancy: normal tissues and some of the benign tumors had the highest levels. PMID: 25985817
亞細(xì)胞定位：

Cell membrane; Multi-pass membrane protein. Cytoplasm.
蛋白家族：

G-protein coupled receptor 1 family
數(shù)據(jù)庫鏈接：

KEGG: cfa:403472

STRING: 9615.ENSCAFP00000006717

UniGene: Cfa.186