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  4. Recombinant Bovine Superoxide dismutase [Mn], mitochondrial (SOD2)

Recombinant Bovine Superoxide dismutase [Mn], mitochondrial (SOD2)

  • 中文名稱：
    牛SOD2重組蛋白
  • 貨號：
    CSB-YP022398BO
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    牛SOD2重組蛋白
  • 貨號：
    CSB-EP022398BO
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    牛SOD2重組蛋白
  • 貨號：
    CSB-EP022398BO-B
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    牛SOD2重組蛋白
  • 貨號：
    CSB-BP022398BO
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    牛SOD2重組蛋白
  • 貨號：
    CSB-MP022398BO
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 別名：
    SOD2; Superoxide dismutase [Mn]; mitochondrial; EC 1.15.1.1
  • 種屬：
    Bos taurus (Bovine)
  • 蛋白長度：
    Full Length of Mature Protein
  • 表達區域：
    25-222
  • 氨基酸序列
    KHSLPD LPYDYGALEP HINAQIMQLH HSKHHAAYVN NLNVAEEKYR EALEKGDVTA QIALQPALKF NGGGHINHSI FWTNLSPNGG GEPQGELLEA IKRDFGSFAK FKEKLTAVSV GVQGSGWGWL GFNKEQGRLQ IAACSNQDPL QGTTGLIPLL GIDVWEHAYY LQYKNVRPDY LKAIWNVINW ENVTARYTAC SK
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.
  • 基因功能參考文獻：
    1. Exposure to follicular fluid transiently increased the transcript levels of IL8 and PTGS2, and decreased the expression of SOD2, GPX3, DAB2, and NR3C1. TNF and IL6 levels were also decreased while those of NAMPT were unaffected. PMID: 24186266
    2. Data suggest that during ectogenesis of blastocysts infected with bovine Herpesvirus type 5, expression of SOD2 (Mn) remains high indicating intense mitochondrial activity; this effect may be involved in inhibition of apoptosis in infected embryos. PMID: 22823939
    3. expression profile of SOD2 in follicles: oocytes (SOD2 restricted to ooplasm); cumulus cells (expressed some SOD2); follicular fluid (small follicles show increased amounts of SOD2 in comparison with large follicles) PMID: 20197373
    4. Shear stress influences spatial variations in vascular Mn-SOD expression with implications for LDL nitration. PMID: 18434620
    5. The expression of SOD1 and SOD2 through the course of the estrous cycle is reported. PMID: 18572235
    6. Heart mitochondrial nucleoids contained SOD2, aortic endothelial cell mitochondrial nucleoids did not PMID: 19228881

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  • 亞細胞定位：
    Mitochondrion matrix.
  • 蛋白家族：
    Iron/manganese superoxide dismutase family
  • 數據庫鏈接：


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