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  4. Recombinant Bartonella henselae Type IV secretion system protein virB4 (virB4), partial

Recombinant Bartonella henselae Type IV secretion system protein virB4 (virB4), partial

  • 中文名稱：
    Recombinant Bartonella henselae Type IV secretion system protein virB4 (virB4), partial
  • 品名簡稱：
    Recombinant Bartonella henselae virB4 protein, partial
  • 貨號：
    CSB-EP870829BSG
  • 說明書：
  • 規(guī)格：
    ￥1536
  • 圖片：
    • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
  • 其他：

產(chǎn)品詳情

  • 純度：
    Greater than 85% as determined by SDS-PAGE.
  • 生物活性：
    Not Test
  • 基因名：
    virB4
  • Uniprot No.：
  • 別名：
    virB4;BH13280
  • 種屬：
    Bartonella henselae (strain ATCC 49882 / DSM 28221 / CCUG 30454 / Houston 1) (Rochalimaea henselae)
  • 蛋白長度：
    Partial
  • 來源：
    E.coli
  • 分子量：
    60.2 kDa
  • 表達區(qū)域：
    1-474aa
  • 氨基酸序列
    MSMMKRESLPEDYIPYIRHINQHVIALNSRCLMTVMVVEGVNFDTADIDQLNSLHNQLNTLLKNIADERVALYSHIIRRRETIYPESQFFSSFAATLDEKYKKKMVSQELYRNDLFVSLLWNPASDKTEQLASFFQRLAKAKKTQSEPDQEAIRKIEELSQDLIEGLESYGARLLSVYAHGGILFSEQSEFLHQLVGGRRERIPLTFGTIASTIYSDRVIFGKETIEIRHESNERFAGMFGWKEYPSKTRPGMTDGLLTAPFEFILTQSFVFKSKAAASVIMGRKQNQMINAADRASSQIEALDEALDDLESNRFVLGEHHLSLAVFANHPKALAEYLSKARAHLTNGGAVIAREDLGLEAAWWAQLPGNFSYRARSGAITSRNFAALSPFHSFPIGKLEGNVWGTAVALLKTQAGSPYYFNFHYGDLGNTFVCGPSGSGKTVIVNFLLAQLQKHNPTMVFFDKDQGAEIFVRA
    Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
    If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
  • 蛋白標簽：
    C-terminal 6xHis-tagged
  • 產(chǎn)品提供形式：
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 緩沖液：
    If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.
  • 復(fù)溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Basically, we can dispatch the products out in 3-7 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • Datasheet & COA：
    Please contact us to get it.

產(chǎn)品評價

靶點詳情

  • 功能：
    The type IV secretion system VirB/VirD4 is a major virulence determinant for subversion of human endothelial cell (HEC) function. VirB-dependent changes of HEC include massive cytoskeletal rearrangements, a proinflammatory activation by nuclear factor NF-kappa-B, inhibition of early and late events of apoptosis, leading to an increased cell survival, and, at high infection doses, a cytostatic or cytotoxic effect, which interfers with a potent VirB-independent mitogenic activity. These changes of HEC require the T4S coupling protein VirD4 and at least one of the effector proteins BepA-G. Altogether with VirB11, may be implicated in providing the energy, via hydrolysis of ATP, for the assembly of secretion system and substrate transport.
  • 亞細胞定位：
    Cell inner membrane.
  • 蛋白家族：
    TrbE/VirB4 family
  • 數(shù)據(jù)庫鏈接：

    KEGG: bhe:BH13280

    STRING: 283166.BH13280