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  4. PDIA4 Recombinant Monoclonal Antibody

PDIA4 Recombinant Monoclonal Antibody

  • 中文名稱：
    PDIA4 Recombinant Monoclonal Antibody
  • 貨號：
    CSB-RA928321A0HU
  • 規格：
    ￥1320
  • 圖片：
    • Immunocytochemical staining of HepG2 cells with PDIA4 antibody. Nuclei were stained blue with DAPI; PDIA4 was stained magenta with Alexa Fluor廬 647. Images were taken using leica stellaris 5. Protein abundance based on laser intensity and smart gain: Medium. Scale bar: 20 渭m.
    • Western blotting analysis using PDIA4 antibody. Total cell lysates (30 μg) from various cell lines were loaded and separated by SDS-PAGE. The blot was incubated with PDIA4 antibody and HRP-conjugated goat anti-rabbit secondary antibody respectively.
  • 其他：

產品詳情

  • Uniprot No.：
  • 基因名：
  • 別名：
    PDIA4; Protein Disulfide Isomerase Family A Member 4; ERP70; ERP72; Endoplasmic Reticulum Resident Protein 70; Endoplasmic Reticulum Resident Protein 72; Protein Disulfide Isomerase-Associated 4; Protein Disulfide-Isomerase A4; ER Protein 70; ER Protein 72; EC 5.3.4.1; ERp-72; Protein Disulfide Isomerase Related Protein (Calcium-Binding Protein, Intestinal-Related); Protein Disulfide Isomerase Family A, Member 4; Testicular Tissue Protein Li 137; ERp70; ERp72
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human PDIA4 protein
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 克隆類型：
    Monoclonal
  • 抗體亞型：
    Rabbit IgG
  • 純化方式：
    Affinity-chromatography
  • 克隆號：
    1E8
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Rabbit IgG in PBS (pH 7.4) containing 50% glycerol, and 0.02% sodium azide.
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA, WB, ICC
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:1000-1:5000
    ICC 1:100-1:1000
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 基因功能參考文獻：
    1. up-regulated by IL11 in first trimester placenta PMID: 28487027
    2. PDIA4 as a negative regulator of cancer cell apoptosis. PMID: 28534513
    3. Participants with metabolic syndrome (MetS) had significantly higher serum PDIA4 levels than those without MetS (P<0.001). After adjustments, the individuals with the highest PDIA4 tertile were associated with a higher risk of MetS than those with the lowest tertile (OR = 4.83, 95% CI: 2.71-8.60). PMID: 28650993
    4. CDDP-resistant non-small lung cancer cells undergo profound remodeling of their endoplasmic reticulum (ER) proteome (>80 proteins identified by proteomics) and exhibit a dramatic overexpression of two protein disulfide isomerases, PDIA4 and PDIA6. PMID: 24464223
    5. novel esophageal squamous cell carcinoma marker PDIA4 was identified by mass spectrometry and immunohistochemical analysis PMID: 21743296
    6. Nox1 associates with ERp72, which involves its N-terminus encompassing a Ca(2+)-binding site and the first TRX-like motif. PMID: 18620548

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  • 亞細胞定位：
    Endoplasmic reticulum lumen. Melanosome.
  • 蛋白家族：
    Protein disulfide isomerase family
  • 數據庫鏈接：

    HGNC: 30167

    KEGG: hsa:9601

    STRING: 9606.ENSP00000286091

    UniGene: Hs.93659