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NUP155 Recombinant Monoclonal Antibody

  • 中文名稱：
    NUP155 Recombinant Monoclonal Antibody
  • 貨號：
    CSB-RA044070A0HU
  • 規格：
    ￥1320
  • 圖片：
    • Flow cytometric analysis of nucleoporin 155 expression in HepG2 cells using nucleoporin 155 antibody. Green, isotype control; red, nucleoporin 155.
    • Western blotting analysis using nucleoporin 155 antibody. Total cell lysates (30 μg) from various cell lines were loaded and separated by SDS-PAGE. The blot was incubated with nucleoporin 155 antibody and HRP-conjugated goat anti-rabbit secondary antibody respectively.
  • 其他：

產品詳情

  • Uniprot No.：
  • 基因名：
    NUP155
  • 別名：
    NUP155; Nucleoporin 155; KIAA0791; N155; Nuclear Pore Complex Protein Nup155; 155 KDa Nucleoporin; Nucleoporin 155kDa; Nucleoporin Nup155; Nucleoporin 155kD; ATFB15
  • 反應種屬：
    Human, Mouse, Rat
  • 免疫原：
    Recombinant Human NUP155 protein
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 克隆類型：
    Monoclonal
  • 抗體亞型：
    Rabbit IgG
  • 純化方式：
    Affinity-chromatography
  • 克隆號：
    14G1
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Rabbit IgG in PBS (pH 7.4) containing 50% glycerol, and 0.02% sodium azide.
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA, WB, FC
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:1000-1:5000
    FC 1:200-1:2000
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Essential component of nuclear pore complex. Could be essessential for embryogenesis. Nucleoporins may be involved both in binding and translocating proteins during nucleocytoplasmic transport.
  • 基因功能參考文獻：
    1. The Nup155-mediated localization was required for HDAC4's effect on gene expression. PMID: 21464227
    2. The Nup155 depletion massively alters nuclear envelope structure, causing a dramatic decrease in Nuclear pore complexes numbers and the improper targeting of membrane proteins to the inner nuclear membrane. PMID: 20974814
    3. These human and mouse studies indicate that loss of NUP155 function causes atrial fibrillation by altering mRNA and protein transport and link the nuclear pore complex to cardiovascular disease. PMID: 19070573
  • 相關疾病：
    Atrial fibrillation, familial, 15 (ATFB15)
  • 亞細胞定位：
    Nucleus, nuclear pore complex. Nucleus membrane; Peripheral membrane protein; Cytoplasmic side. Nucleus membrane; Peripheral membrane protein; Nucleoplasmic side.
  • 蛋白家族：
    Non-repetitive/WGA-negative nucleoporin family
  • 組織特異性：
    Expressed in all tissues tested, including heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas.
  • 數據庫鏈接：

    HGNC: 8063

    OMIM: 606694

    KEGG: hsa:9631

    STRING: 9606.ENSP00000231498

    UniGene: Hs.547696