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  4. HSPA14 Recombinant Monoclonal Antibody

HSPA14 Recombinant Monoclonal Antibody

  • 中文名稱：
    HSPA14 Recombinant Monoclonal Antibody
  • 貨號：
    CSB-RA231037A0HU
  • 規格：
    ￥1320
  • 圖片：
    • Western blotting analysis using HSPA14 antibody. Total cell lysates (30 μg) from various cell lines were loaded and separated by SDS-PAGE. The blot was incubated with HSPA14 antibody and HRP-conjugated goat anti-rabbit secondary antibody respectively.
    • Flow cytometric analysis of HSPA14 expression in HAP-1 cells using HSPA14 antibody. Green, isotype control; red, HSPA14.
    • Immunocytochemical staining of HAP-1 cells with HSPA14 antibody. Nuclei were stained blue with DAPI; HSPA14 was stained magenta with Alexa Fluor? 647. Images were taken using Leica stellaris 5. Protein abundance based on laser Intensity and smart gain: Medium. Scale bar, 20 μm.
  • 其他：

產品詳情

  • Uniprot No.：
  • 基因名：
  • 別名：
    HSPA14; Heat Shock Protein Family A (Hsp70) Member 14; HSP70L1; HSP70-4; Heat Shock 70 KDa Protein 14; Heat Shock Protein HSP60; HSP70-Like Protein 1; Heat Shock Protein Hsp70-Related Protein; Heat Shock 70kDa Protein 14; MSANTD7; HSP60
  • 反應種屬：
    Human, Mouse, Rat
  • 免疫原：
    Recombinant Human HSPA14 protein
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 克隆類型：
    Monoclonal
  • 抗體亞型：
    Rabbit IgG
  • 純化方式：
    Affinity-chromatography
  • 克隆號：
    12A1
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Rabbit IgG in PBS (pH 7.4) containing 50% glycerol, and 0.02% sodium azide.
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA, WB, ICC
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:1000-1:5000
    ICC 1:100-1:1000
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Component of the ribosome-associated complex (RAC), a complex involved in folding or maintaining nascent polypeptides in a folding-competent state. In the RAC complex, binds to the nascent polypeptide chain, while DNAJC2 stimulates its ATPase activity.
  • 基因功能參考文獻：
    1. TLR4 is a key receptor mediating the interaction of Hsp70L1 with DCs and subsequently enhancing the induction of Th1 immune response by Hsp70L1/antigen fusion protein PMID: 21730052
    2. a novel pathway (NBS1-HSF4b-HSPA4/HSPA14 axis) to induce migration, invasion, and transformation, suggesting the activation of multiple signaling events induced by NBS1 overexpression PMID: 21208456
    3. results demonstrate that Hsp70L1 has enhanced Th1 polarizing and adjuvant properties, which appear to be mediated via activation of dendritic cells PMID: 14592822
  • 亞細胞定位：
    Cytoplasm, cytosol.
  • 蛋白家族：
    Heat shock protein 70 family
  • 數據庫鏈接：

    HGNC: 29526

    OMIM: 610369

    KEGG: hsa:51182

    STRING: 9606.ENSP00000367623

    UniGene: Hs.534169



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