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CDC123 Recombinant Monoclonal Antibody

  • 中文名稱：
    CDC123 Recombinant Monoclonal Antibody
  • 貨號：
    CSB-RA193296A0HU
  • 規格：
    ￥1320
  • 圖片：
    • Flow cytometric analysis of CDC123 expression in HAP-1 cells using CDC123 antibody. Green, isotype control; red, CDC123.
    • Immunocytochemical staining of HAP1 cells with CDC123 antibody. Nuclei were stained blue with DAPI;CDC123 was stained magenta with Alexa Fluor? 647. Images were taken using Leica stellaris 5. Protein abundance based on laser Intensity and smart gain: Medium. Scale bar, 20 μm.
    • Western blotting analysis using CDC123 antibody. Total cell lysates (30 μg) from various cell lines were loaded and separated by SDS-PAGE. The blot was incubated with CDC123 antibody and HRP-conjugated goat anti-rabbit secondary antibody respectively.
  • 其他：

產品詳情

  • Uniprot No.：
  • 基因名：
  • 別名：
    CDC123; Cell Division Cycle 123; D123; Cell Division Cycle Protein 123 Homolog; C10orf7; HT-1080; PZ32; Cell Division Cycle 123 Homolog (S. Cerevisiae); Chromosome 10 Open Reading Frame 7; Cell Division Cycle 123 Homolog; Protein D123; C10ORF7
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human CDC123 protein
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 克隆類型：
    Monoclonal
  • 抗體亞型：
    Rabbit IgG
  • 純化方式：
    Affinity-chromatography
  • 克隆號：
    8G4
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Rabbit IgG in PBS (pH 7.4) containing 50% glycerol, and 0.02% sodium azide.
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA, WB, FC, ICC
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:1000-1:5000
    FC 1:200-1:2000
    ICC 1:100-1:1000
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Required for S phase entry of the cell cycle.
  • 基因功能參考文獻：
    1. There were no statistically significant differences in the distribution of CDC123/CAMK1D rs12779790 genotypes and alleles between women with gestational diabetes mellitus and healthy pregnant women. PMID: 28079868
    2. CDC123 may have a role in novel protein modifications PMID: 25976611
    3. Association to type 2 diabetes was found for rs13266634 (SLC30A8), rs7923837 (HHEX), rs10811661 (CDKN2A/2B), rs4402960 (IGF2BP2), rs12779790 (CDC123/CAMK1D), and rs2237892 (KCNQ1). PMID: 22923468
    4. A significant association of rs10906115 in CDC123/CAMK1D and rs1359790 near SPRY2 was identified with type 2 diabetes in a Japanese population. PMID: 21909839
  • 亞細胞定位：
    Cytoplasm.
  • 蛋白家族：
    CDC123 family
  • 組織特異性：
    Widely expressed. Expressed in spleen, thymus, prostate, testis, ovary, small intestine, colon and leukocytes with the highest expression in testis.
  • 數據庫鏈接：

    HGNC: 16827

    OMIM: 617708

    KEGG: hsa:8872

    STRING: 9606.ENSP00000281141

    UniGene: Hs.412842