国产午夜福利片1000无码丨人妻国产成人久久av免费高清丨午夜做受视频试看6次丨日韩av不卡一区在线免费观看丨在线观看精品三级欧美

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 重組抗體
  4. ATP1B3 Recombinant Monoclonal Antibody

ATP1B3 Recombinant Monoclonal Antibody

  • 中文名稱：
    ATP1B3 Recombinant Monoclonal Antibody
  • 貨號：
    CSB-RA286719A0HU
  • 規格：
    ￥1320
  • 圖片：
    • Western blotting analysis using ATP1B3 antibody. Total cell lysates (30 μg) from various cell lines were loaded and separated by SDS-PAGE. The blot was incubated with ATP1B3 antibody and HRP-conjugated goat anti-rabbit secondary antibody respectively.
  • 其他：

產品詳情

  • Uniprot No.：
  • 基因名：
  • 別名：
    ATP1B3; ATPase Na+/K+ Transporting Subunit Beta 3; Sodium/Potassium-Transporting ATPase Subunit Beta-3; CD298; Sodium-Potassium ATPase Subunit Beta 3 (Non-Catalytic); Sodium/Potassium-Dependent ATPase Subunit Beta-3; ATPase, Na+/K+ Transporting, Beta 3 Polypeptide; Sodium Pump Subunit Beta-3; FLJ29027; ATPB-3; Sodium/Potassium-Transporting ATPase Beta-3 Chain; Na, K-ATPase Beta-3 Polypeptide; CD298 Antigen
  • 反應種屬：
    Human, Mouse, Rat
  • 免疫原：
    Recombinant Human ATP1B3 protein
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 克隆類型：
    Monoclonal
  • 抗體亞型：
    Rabbit IgG
  • 純化方式：
    Affinity-chromatography
  • 克隆號：
    21A3
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Rabbit IgG in PBS (pH 7.4) containing 50% glycerol, and 0.02% sodium azide.
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA, WB
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:1000-1:5000
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. The exact function of the beta-3 subunit is not known.
  • 基因功能參考文獻：
    1. ligation of the Na, K ATPase beta3 subunit on monocytes by mAb P-3E10 arbitrated T cell hypofunction. This mAb might be a promising novel immunotherapeutic antibody for the treatment of hyperresponsive T cell associated diseases. PMID: 29940031
    2. Our study demonstrated that ATP1B3 inhibit EV71 replication by enhancing the production of type-I interferons, which could act as a potential therapeutic target in EV71 infection. PMID: 27240146
    3. Data suggest that ATP1B3 is binding partner of BST-2 and regulates stability of BST-2; ATP1B3 is co-factor that accelerates BST-2 degradation and reduces BST-2-mediated restriction of HIV-1 replication/tropism and NFkappaB activation. PMID: 26694617
    4. B7H3 and ATP1B3 are overexpressed in tumor endothelial cells, favoring an angiogenic phenotype. PMID: 24236063
    5. role in T and B lymphocyte activation PMID: 12456588
    6. These results evidenced that the beta3 subunit of Na, K ATPase is expressed on RBC membrane but the epitope recognized by mAb P-3E10 is hidden in normal RBCs. we showed the association of beta3 subunit and alpha subunit of Na, K ATPase. PMID: 17176442

    顯示更多

    收起更多

  • 亞細胞定位：
    Apical cell membrane; Single-pass type II membrane protein. Basolateral cell membrane; Single-pass type II membrane protein. Melanosome. Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
  • 蛋白家族：
    X(+)/potassium ATPases subunit beta family
  • 數據庫鏈接：

    HGNC: 806

    OMIM: 601867

    KEGG: hsa:483

    STRING: 9606.ENSP00000286371

    UniGene: Hs.477789