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AP3M1 Recombinant Monoclonal Antibody

  • 中文名稱：
    AP3M1 Recombinant Monoclonal Antibody
  • 貨號：
    CSB-RA165753A0HU
  • 規格：
    ￥1320
  • 圖片：
    • Western blotting analysis using AP3M1 antibody. Total cell lysates (30 μg) from various cell lines were loaded and separated by SDS-PAGE. The blot was incubated with AP3M1 antibody and HRP-conjugated goat anti-rabbit secondary antibody respectively.
  • 其他：

產品詳情

  • Uniprot No.：
  • 基因名：
    AP3M1
  • 別名：
    AP3M1; Adaptor Related Protein Complex 3 Subunit Mu 1; Adaptor Related Protein Complex 3 Mu 1 Subunit; AP-3 Complex Subunit Mu-1; Mu-Adaptin 3A; Mu3A-Adaptin; Adapter-Related Protein Complex 3 Mu-1 Subunit; Adaptor-Related Protein Complex 3 Subunit Mu-1; Clathrin Adaptor Complex AP3, Mu-3A Subunit; AP-3 Adapter Complex Mu3A Subunit; AP-3 Adaptor Complex Mu3A Subunit
  • 反應種屬：
    Human, Mouse, Rat
  • 免疫原：
    Recombinant Human AP3M1 protein
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 克隆類型：
    Monoclonal
  • 抗體亞型：
    Rabbit IgG
  • 純化方式：
    Affinity-chromatography
  • 克隆號：
    8C6
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Rabbit IgG in PBS (pH 7.4) containing 50% glycerol, and 0.02% sodium azide.
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA, WB
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:1000-1:5000
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes. In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals.
  • 基因功能參考文獻：
    1. Structural basis for the recognition of tyrosine-based sorting signals by the mu3A subunit of the AP-3 adaptor complex PMID: 23404500
    2. results demonstrate that the intact and stable AP-3 complex is required for HIV-1 assembly and release, and the involvement of the AP-3 complex in late stages of the HIV-1 replication cycle is independent of clathrin-mediated endocytosis PMID: 22875976
    3. The present results suggest that AP3 complex genes might not play a major role in the pathogenesis of schizophrenia. PMID: 19481122
  • 亞細胞定位：
    Golgi apparatus. Cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side.
  • 蛋白家族：
    Adaptor complexes medium subunit family
  • 數據庫鏈接：

    HGNC: 569

    OMIM: 610366

    KEGG: hsa:26985

    STRING: 9606.ENSP00000347408

    UniGene: Hs.500104