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  4. ACAP2 Recombinant Monoclonal Antibody

ACAP2 Recombinant Monoclonal Antibody

  • 中文名稱：
    ACAP2 Recombinant Monoclonal Antibody
  • 貨號：
    CSB-RA105712A0HU
  • 規格：
    ￥1320
  • 圖片：
    • Flow cytometric analysis of ACAP2 expression in HT-1080 cells using ACAP2 antibody. Green, isotype control; red, ACAP2.
    • Immunocytochemical staining of HT-1080 cells with ACAP2 antibody. Nuclei were stained blue with DAPI; ACAP2 was stained magenta with Alexa Fluor? 647. Images were taken using Leica stellaris 5. Protein abundance based on laser Intensity and smart gain: High. Scale bar, 20 μm.
    • Western blotting analysis using ACAP2 antibody. Total cell lysates (30 μg) from various cell lines were loaded and separated by SDS-PAGE. The blot was incubated with ACAP2 antibody and HRP-conjugated goat anti-rabbit secondary antibody respectively.
  • 其他：

產品詳情

  • Uniprot No.：
  • 基因名：
  • 別名：
    ACAP2; ArfGAP With Coiled-Coil, Ankyrin Repeat And PH Domains 2; KIAA0041; CNT-B2; CENTB2; Arf-GAP With Coiled-Coil, ANK Repeat And PH Domain-Containing Protein 2; Centaurin-Beta-2; Arf GAP With Coiled Coil, ANK Repeat And PH Domains 2; Centaurin, Beta 2; Cnt-B2
  • 反應種屬：
    Human, Mouse, Rat
  • 免疫原：
    Recombinant Human ACAP2 protein
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 克隆類型：
    Monoclonal
  • 抗體亞型：
    Rabbit IgG
  • 純化方式：
    Affinity-chromatography
  • 克隆號：
    19E10
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Rabbit IgG in PBS (pH 7.4) containing 50% glycerol, and 0.02% sodium azide.
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA, WB, FC, ICC
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:1000-1:5000
    FC 1:200-1:2000
    ICC 1:100-1:1000
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    GTPase-activating protein (GAP) for ADP ribosylation factor 6 (ARF6).
  • 基因功能參考文獻：
    1. The down-regulation of circRNA-ACAP2 promoted miR-21-5p expression, which further suppressed the transcription and translation of Tiam1. PMID: 30212824
    2. ACAP2 is a functional homolog of C. elegans CNT-1 and its inactivation or downregulation in human cells may contribute to cancer development PMID: 25853217
    3. ACAP2 has robust, constitutive Arf6 GAP activity in vivo, with little activity toward Arf1. PMID: 18003747
    4. Centaurin beta2/KIAA0041, is a member of the centaurin family of ADP-ribosylation factor directed GTPase-activating proteins. Binding of phosphoinositides to a pleckstrin homology domain may regulate subcellular localisation and activity. PMID: 11050434
  • 亞細胞定位：
    Endosome membrane; Peripheral membrane protein.
  • 組織特異性：
    Widely expressed. Highest level in lung.
  • 數據庫鏈接：

    HGNC: 16469

    OMIM: 607766

    KEGG: hsa:23527

    STRING: 9606.ENSP00000324287

    UniGene: Hs.593373