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gB Antibody

Rare Species
  • 中文名稱：
    gB兔多克隆抗體
  • 貨號：
    CSB-PA355975ZA01EFA
  • 規(guī)格：
    ￥440
  • 圖片：
    • Western Blot
      Positive WB detected in Recombinant protein
      All lanes: gB antibody at 1:2000
      Secondary
      Goat polyclonal to rabbit IgG at 1/50000 dilution
      Predicted band size: 43.3 kDa
      Observed band size: 46 kDa
  • 其他：

產(chǎn)品詳情

  • Uniprot No.：
  • 基因名：
    gB
  • 別名：
    Envelope glycoprotein B (gB), gB
  • 反應(yīng)種屬：
    Epstein-Barr virus
  • 免疫原：
    Recombinant Epstein-Barr virus gB protein (23-260aa)
  • 免疫原種屬：
    Epstein-Barr virus
  • 標記方式：
    Non-conjugated
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    Protein G
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA, WB
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 功能：
    Envelope glycoprotein that forms spikes at the surface of virion envelope. Essential for the initial attachment to heparan sulfate moieties of the host cell surface proteoglycans. Involved in fusion of viral and cellular membranes leading to virus entry into the host cell. Following initial binding to its host receptors, membrane fusion is mediated by the fusion machinery composed at least of gB and the heterodimer gH/gL. May be involved in the fusion between the virion envelope and the outer nuclear membrane during virion egress.
  • 基因功能參考文獻：
    1. These studies indicate that the cytoplasmic tail domain is important in the cellular localization, expression, and fusion function of Epstein-Barr virus gB. PMID: 23341550
    2. These data demonstrate that the bulky and hydrophobic EBV loop residues, which differ from the more hydrophilic HSV-1 residues and appear more compatible with membrane insertion, are essential for EBV gB-dependent fusion. PMID: 17553877
    3. Fusion activity was abolished in all but three variants containing mutations in the N-terminal region (gB30), within the ectodomain (gB421), and in the intracellular C-terminal domain (gB832) of the protein. PMID: 18987135
  • 亞細胞定位：
    Virion membrane; Single-pass type I membrane protein. Host cell membrane; Single-pass type I membrane protein. Host endosome membrane; Single-pass type I membrane protein. Host Golgi apparatus membrane; Single-pass type I membrane protein.
  • 蛋白家族：
    Herpesviridae glycoprotein B family
  • 數(shù)據(jù)庫鏈接：

    KEGG: vg:3783680



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