国产午夜福利片1000无码丨人妻国产成人久久av免费高清丨午夜做受视频试看6次丨日韩av不卡一区在线免费观看丨在线观看精品三级欧美

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. ZDHHC20 Antibody, Biotin conjugated

ZDHHC20 Antibody, Biotin conjugated

  • 中文名稱：
    ZDHHC20兔多克隆抗體, Biotin偶聯
  • 貨號：
    CSB-PA722800LD01HU
  • 規格：
    ￥880
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) ZDHHC20 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    ZDHHC20
  • 別名：
    ZDHHC20; Palmitoyltransferase ZDHHC20; Acyltransferase ZDHHC20; DHHC domain-containing cysteine-rich protein 20; DHHC20; Zinc finger DHHC domain-containing protein 20
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Probable palmitoyltransferase ZDHHC20 protein (75-130AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Biotin
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Palmitoyltransferase that could catalyze the addition of palmitate onto various protein substrates. Catalyzes palmitoylation of Cys residues in the cytoplasmic C-terminus of EGFR, and modulates the duration of EGFR signaling by modulating palmitoylation-dependent EGFR internalization and degradation. Has a preference for acyl-CoA with C16 fatty acid chains. Can also utilize acyl-CoA with C14 and C18 fatty acid chains.
  • 基因功能參考文獻：
    1. crystal structure determined; active site resides at the membrane-cytosol interface; acyl chain binds in a cavity formed by the transmembrane domain; propose a mechanism for acyl chain-length selectivity in DHHC enzymes on the basis of cavity mutants with preferences for shorter and longer acyl chains PMID: 29326245
    2. Targeting of a peripheral modulator of EGFR signaling, DHHC20, causes a loss of signal regulation and susceptibility to EGFR inhibitor-induced cell death. PMID: 27153536
    3. DHHC20 is a human N-terminal-myristoyl-directed palmitoyl acyltransferase involved in cellular transformation, that may play a role in cancer. PMID: 20334580
  • 亞細胞定位：
    Golgi apparatus membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. Cytoplasm, perinuclear region.
  • 蛋白家族：
    DHHC palmitoyltransferase family
  • 數據庫鏈接：

    HGNC: 20749

    KEGG: hsa:253832

    STRING: 9606.ENSP00000371905

    UniGene: Hs.564611



主站蜘蛛池模板： 林西县| 清丰县| 灵丘县| 湖州市| 翁牛特旗| 平武县| 通化县| 福建省| 襄樊市| 安岳县| 威信县| 留坝县| 兰坪| 阿拉善左旗| 日喀则市| 镇安县| 石楼县| 永年县| 靖安县| 泰宁县| 汶川县| 定陶县| 汝城县| 抚州市| 赫章县| 宁德市| 元谋县| 洪江市| 汝阳县| 监利县| 房山区| 如皋市| 漾濞| 武城县| 呼伦贝尔市| 荔浦县| 溧阳市| 禹城市| 毕节市| 随州市| 古丈县|