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  4. XAB2 Antibody, Biotin conjugated

XAB2 Antibody, Biotin conjugated

  • 中文名稱：
    XAB2兔多克隆抗體, Biotin偶聯
  • 貨號：
    CSB-PA862073LD01HU
  • 規格：
    ￥880
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) XAB2 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    XAB2
  • 別名：
    0610041O14Rik antibody; adapter protein ATH 55 antibody; Adapter protein ATH-55 antibody; Ath55 antibody; AV025587 antibody; Crn related protein kim1 antibody; crn-related protein kim1 antibody; DKFZp762C1015 antibody; HCNP antibody; HCNP protein antibody; HCRN antibody; KIAA1177 antibody; NTC90 antibody; PP3898 antibody; Pre-mRNA-splicing factor SYF1 antibody; Protein HCNP antibody; RNA splicing factor antibody; SYF1 antibody; SYF1 homolog antibody; SYF1 homolog, RNA splicing factor antibody; SYF1 pre mRNA splicing factor antibody; SYF1_HUMAN antibody; Xab2 antibody; XPA binding protein 2 antibody; XPA-binding protein 2 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Pre-mRNA-splicing factor SYF1 protein (750-840AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Biotin
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Involved in pre-mRNA splicing as component of the spliceosome. Involved in transcription-coupled repair (TCR), transcription and pre-mRNA splicing.
  • 基因功能參考文獻：
    1. these results support a novel function of XAB2 in mitotic cell cycle regulation, which is partially mediated by transcription regulation on CENPE. PMID: 27735937
    2. we suggest that the XAB2 complex mediates DNA damage response events important for the end resection step of homologous recombination , and speculate that its adjacent-localization relative to double-strand break marked by gH2AX is important for this function PMID: 27084940
    3. Study identifies XAB2 tagSNPs (rs794078 and rs4134816) significantly associated with the risk of non-small cell lung cancer (NSCLC) in Chinese population, which supports XAB2 playing significant role in the development of NSCLC. PMID: 26228655
    4. Hematopoietic myeloid cell differentiation diminishes nucleotide excision repair and XAB2 expression. PMID: 25027282
    5. XAB2 complex is a multifunctional factor involved in pre-mRNA splicing, transcription, and transcription-coupled DNA repair. PMID: 17981804

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  • 亞細胞定位：
    Nucleus.
  • 蛋白家族：
    Crooked-neck family
  • 數據庫鏈接：

    HGNC: 14089

    OMIM: 610850

    KEGG: hsa:56949

    STRING: 9606.ENSP00000351137

    UniGene: Hs.9822



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