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UAP1 Antibody, Biotin conjugated

  • 中文名稱：
    UAP1兔多克隆抗體, Biotin偶聯
  • 貨號：
    CSB-PA618067LD01HU
  • 規格：
    ￥880
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) UAP1 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    UAP1
  • 別名：
    AGX 1 antibody; AGX antibody; AGX-1 antibody; AGX-2 antibody; AGX1 antibody; Antigen X antibody; AntigenX antibody; SPAG 2 antibody; SPAG2 antibody; Sperm associated antigen 2 antibody; Sperm-associated antigen 2 antibody; UAP 1 antibody; uap1 antibody; UAP1_HUMAN antibody; UDP N acetylhexosamine pyrophosphorylase antibody; UDP N acteylglucosamine pyrophosphorylase 1 antibody; UDP-N-acetylglucosamine pyrophosphorylase antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human UDP-N-acetylhexosamine pyrophosphorylase protein (1-522AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Biotin
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Converts UTP and GlcNAc-1-P into UDP-GlcNAc, and UTP and GalNAc-1-P into UDP-GalNAc. Isoform AGX1 has 2 to 3 times higher activity towards GalNAc-1-P, while isoform AGX2 has 8 times more activity towards GlcNAc-1-P.
  • 基因功能參考文獻：
    1. Results identified an enzyme, UAP1, which is highly overexpressed in prostate cancer and protects cancer cells from endoplasmic reticulum stress conferring a growth advantage. PMID: 25241896
  • 亞細胞定位：
    Cytoplasm. Note=In spermatozoa, localized to the principal piece of the tail, the neck region of the head and to a lesser extent, the midpiece of the tail.
  • 蛋白家族：
    UDPGP type 1 family
  • 組織特異性：
    Widely expressed. Isoform AGX1 is more abundant in testis than isoform AGX2, while isoform AGX2 is more abundant than isoform AGX1 in somatic tissue. Expressed at low level in placenta, muscle and liver.
  • 數據庫鏈接：

    HGNC: 12457

    OMIM: 602862

    KEGG: hsa:6675

    STRING: 9606.ENSP00000356903

    UniGene: Hs.492859