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TMEM106A Antibody, FITC conjugated

  • 中文名稱：
    TMEM106A兔多克隆抗體, FITC偶聯
  • 貨號：
    CSB-PA023673LC01HU
  • 規格：
    ￥880
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) TMEM106A Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    TMEM106A
  • 別名：
    TMEM106A; Transmembrane protein 106A
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Transmembrane protein 106A protein (1-94AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    FITC
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式：
    Liquid
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Activates macrophages and polarizes them into M1-like macrophages through the activation of the MAPK and NF-kappaB signaling pathway. Upon activation, upregulates the expression of CD80, CD86, CD69 and MHC II on macrophages, and induces the release of pro-inflammatory cytokines such as TNF, IL1B, IL6, CCL2 and nitric oxide. May play a role in inhibition of proliferation and migration.
  • 基因功能參考文獻：
    1. Low TMEM106A expression is associated with gastric cancer. PMID: 24975047
  • 亞細胞定位：
    Cell membrane; Single-pass membrane protein.
  • 蛋白家族：
    TMEM106 family
  • 組織特異性：
    Expressed in renal cells (at protein level). Expressed in epithelial cells.
  • 數據庫鏈接：

    HGNC: 28288

    KEGG: hsa:113277

    UniGene: Hs.536474