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TESPA1 Antibody

  • 中文名稱：
    TESPA1兔多克隆抗體
  • 貨號：
    CSB-PA012205LA01HU
  • 規格：
    ￥440
  • 圖片：
    • Immunohistochemistry of paraffin-embedded human small intestine tissue using CSB-PA012205LA01HU at dilution of 1:100
    • Immunofluorescent analysis of A549 cells using CSB-PA012205LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) TESPA1 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    TESPA1
  • 別名：
    TESPA1 antibody; KIAA0748 antibody; HSPC257Protein TESPA1 antibody; Thymocyte-expressed positive selection-associated protein 1 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Protein TESPA1 protein (251-521AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated

    本頁面中的產品，TESPA1 Antibody (CSB-PA012205LA01HU)，的標記方式是Non-conjugated。對于TESPA1 Antibody，我們還提供其他標記。見下表：

    可提供標記
    標記方式 貨號 產品名稱 應用
    HRP CSB-PA012205LB01HU TESPA1 Antibody, HRP conjugated ELISA
    FITC CSB-PA012205LC01HU TESPA1 Antibody, FITC conjugated
    Biotin CSB-PA012205LD01HU TESPA1 Antibody, Biotin conjugated ELISA
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA, IHC, IF
  • 推薦稀釋比：
    Application Recommended Dilution
    IHC 1:20-1:200
    IF 1:50-1:200
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Required for the development and maturation of T-cells, its function being essential for the late stages of thymocyte development. Plays a role in T-cell antigen receptor (TCR)-mediated activation of the ERK and NFAT signaling pathways, possibly by serving as a scaffolding protein that promotes the assembly of the LAT signalosome in thymocytes. May play a role in the regulation of inositol 1,4,5-trisphosphate receptor-mediated Ca(2+) release and mitochondrial Ca(2+) uptake via the mitochondria-associated endoplasmic reticulum membrane (MAM) compartment.
  • 基因功能參考文獻：
    1. Tespa1 functions in T cell development and the regulation of TCR-induced Ca(2+) signalling through IP3R1 PMID: 28598420
    2. Tespa1 hay have a role in susceptibility but not severity of rheumatoid arthritis in the Zhejiang Han population in China PMID: 25736038
    3. The TESPA1 gene was found to not be involved in ankylosing spondylitis in a Chinese population. PMID: 24893580
    4. Tespa1 is post-translationally modified upon intracellular divalent calcium-ion Ca2+ increase in thymocytes. PMID: 23541577
    5. Tespa1 is a novel component of mitochondria-associated endoplasmic reticulum membranes and affects mitochondrial calcium flux. PMID: 23501103

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  • 亞細胞定位：
    Cytoplasm. Endoplasmic reticulum membrane.
  • 數據庫鏈接：

    HGNC: 29109

    OMIM: 615664

    KEGG: hsa:9840

    STRING: 9606.ENSP00000312679

    UniGene: Hs.33187